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HACD1
Description
3-hydroxyacyl-CoA dehydratase 1
Image
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Membrane
Molecular Function
Protein Binding
Lyase Activity
3-hydroxyacyl-CoA Dehydratase Activity
Enzyme Binding
Hydroxyapatite Binding
Very-long-chain (3R)-3-hydroxyacyl-CoA Dehydratase Activity
Biological Process
Lipid Metabolic Process
Fatty Acid Metabolic Process
Fatty Acid Biosynthetic Process
Positive Regulation Of Cell-substrate Adhesion
Sphingolipid Biosynthetic Process
Fatty Acid Elongation
Long-chain Fatty-acyl-CoA Biosynthetic Process
Very Long-chain Fatty Acid Biosynthetic Process
Protein-containing Complex Assembly
Cementum Mineralization
Pathways
Synthesis of very long-chain fatty acyl-CoAs
Drugs
Diseases
GWAS
Novel Interacting Genes
1 novel interacting genes:
GATA3
Interacting Genes
7 interacting genes:
CPLX4
IL10RA
LMNA
RNF170
TECR
TMEM106C
UBC
Entrez ID
9200
HPRD ID
10175
Ensembl ID
ENSG00000165996
Uniprot IDs
B0YJ81
PDB IDs
Enriched GO Terms of Interacting Partners
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Regulation Of Cellular Response To X-ray
Negative Regulation Of Glial Cell-derived Neurotrophic Factor Receptor Signaling Pathway Involved In Ureteric Bud Formation
Type IV Hypersensitivity
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Ureteric Bud Formation
Negative Regulation Of Cell Proliferation Involved In Mesonephros Development
Interleukin-10 Binding
Pro-T Cell Differentiation
Parathyroid Hormone Secretion
Interleukin-10 Receptor Activity
DNA Double-strand Break Attachment To Nuclear Envelope
Structural Constituent Of Nuclear Lamina
Endoplasmic Reticulum Membrane
Very-long-chain Enoyl-CoA Reductase Activity
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