MTRFR

Description		mitochondrial translation release factor in rescue
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix
	Molecular Function	TRNA Binding RNA Binding Translation Release Factor Activity Protein Binding Translation Release Factor Activity, Codon Specific Ribosomal Large Subunit Binding
	Biological Process	Translation Translational Termination Rescue Of Stalled Ribosome
Pathways		Mitochondrial ribosome-associated quality control
Drugs
Diseases		Combined oxidative phosphorylation deficiency (COXPD)
GWAS
Novel Interacting Genes		4 novel interacting genes: CCDC62 KDM2B RFLNA TMEM120B
Interacting Genes		2 interacting genes: APP CDK2
Entrez ID		91574
HPRD ID		08791
Ensembl ID		ENSG00000130921
Uniprot IDs		Q9H3J6
PDB IDs		7A5H
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Chromatin Remodeling Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Reproductive Process Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Chromatin Organization Y Chromosome Positive Regulation Of Heterochromatin Formation Cyclin A1-CDK2 Complex Cyclin-dependent Protein Kinase Activity Cyclin A2-CDK2 Complex Cyclin E1-CDK2 Complex Cyclin E2-CDK2 Complex Positive Regulation Of DNA-templated DNA Replication Initiation Initiation Of Neural Tube Closure Midbrain-hindbrain Boundary Morphogenesis Fourth Ventricle Development Negative Regulation Of Chondrocyte Development Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling X Chromosome Histone H3K36me/H3K36me2 Demethylase Activity Negative Regulation Of Bone Mineralization Involved In Bone Maturation Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Third Ventricle Development Regulation Of Spontaneous Synaptic Transmission Chromatin Organization NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity
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