CCNB2

Description		cyclin B2
Image		No pdb structure
GO Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Cytoplasm Centrosome Microtubule Organizing Center Cytosol Microtubule Cytoskeleton Membrane
	Molecular Function	Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity Cadherin Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle In Utero Embryonic Development Spindle Assembly Involved In Female Meiosis I G2/MI Transition Of Meiotic Cell Cycle Regulation Of Growth T Cell Homeostasis Mitotic Cell Cycle Phase Transition Thymus Development Cell Division
Pathways		Polo-like kinase mediated events Golgi Cisternae Pericentriolar Stack Reorganization Resolution of Sister Chromatid Cohesion Condensation of Prometaphase Chromosomes Regulation of PLK1 Activity at G2/M Transition Activation of NIMA Kinases NEK9, NEK6, NEK7 Initiation of Nuclear Envelope (NE) Reformation Nuclear Pore Complex (NPC) Disassembly Cyclin A/B1/B2 associated events during G2/M transition G2/M DNA replication checkpoint The role of GTSE1 in G2/M progression after G2 checkpoint
Drugs
Diseases
GWAS		Metabolite levels ( 22916037)
Interacting Genes		7 interacting genes: CDK1 CDK2 CDKN1A CKS1B CKS2 MCM2 TGFBR2
Entrez ID		9133
HPRD ID		04131
Ensembl ID		ENSG00000157456
Uniprot IDs		O95067
PDB IDs
Enriched GO Terms of Interacting Partners?		Cyclin-dependent Protein Kinase Holoenzyme Complex Regulation Of DNA Replication Cyclin Binding Mitotic Cell Cycle Phase Transition Fibroblast Proliferation Regulation Of Mitotic Cell Cycle Positive Regulation Of DNA Replication Cyclin-dependent Protein Kinase Activity Cell Cycle Phase Transition Mitotic DNA Damage Checkpoint Signaling Histone Kinase Activity Mitotic DNA Integrity Checkpoint Signaling G1/S Transition Of Mitotic Cell Cycle Cell Cycle G1/S Phase Transition DNA Damage Checkpoint Signaling Regulation Of G2/M Transition Of Mitotic Cell Cycle Cyclin-dependent Protein Serine/threonine Kinase Activator Activity Regulation Of Cell Cycle G2/M Phase Transition Cell Division Regulation Of Cell Cycle Mitotic G1 DNA Damage Checkpoint Signaling Regulation Of DNA-templated DNA Replication Initiation Mitotic G1/S Transition Checkpoint Signaling DNA Replication Regulation Of DNA Metabolic Process Signal Transduction In Response To DNA Damage Negative Regulation Of Mitotic Cell Cycle Phase Transition Histone Binding Chromosome, Telomeric Region Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Mitotic Cell Cycle Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity Negative Regulation Of Cell Cycle Phase Transition Mitotic G2 DNA Damage Checkpoint Signaling Cell Population Proliferation Negative Regulation Of Cell Cycle Process DNA Damage Response Positive Regulation Of DNA Metabolic Process Intracellular Signaling Cassette G2/M Transition Of Mitotic Cell Cycle Mitotic G2/M Transition Checkpoint Cell Cycle G2/M Phase Transition Positive Regulation Of Cell Population Proliferation Regulation Of Mitotic Cell Cycle Phase Transition SCF Ubiquitin Ligase Complex Negative Regulation Of Cell Cycle Cellular Senescence Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of Cell Cycle G1/S Phase Transition
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