SPAG9

Gene Name		sperm associated antigen 9
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Gene Ontology Annotations	Cellular Component	Acrosomal Vesicle Cytoplasm Cytosol Integral Component Of Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	MAP-kinase Scaffold Activity Protein Binding JUN Kinase Binding Kinesin Binding Receptor Signaling Complex Scaffold Activity Mitogen-activated Protein Kinase P38 Binding
	Biological Process	Activation Of JUN Kinase Activity Spermatogenesis Positive Regulation Of Cell Migration Retrograde Transport, Endosome To Golgi Muscle Cell Differentiation Positive Regulation Of Neuron Differentiation Striated Muscle Cell Differentiation Positive Regulation Of Muscle Cell Differentiation Protein Homooligomerization Negative Regulation Of Protein Homodimerization Activity
Pathways		CDO in myogenesis Myogenesis
Drugs
Diseases
GWAS
Protein-protein Interactions		11 interactors: KLC1 MAP1LC3B MAP2K4 MAP3K3 MAPK14 MAPK8 MAX MYC NFKB1 PNRC2 TP53BP1
Entrez ID		9043
HPRD ID		10398
Ensembl ID		ENSG00000008294
Uniprot IDs		O60271 Q5JB53
PDB IDs		2W83
Enriched GO Terms of Interacting Partners?		Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway MAPK Cascade Toll-like Receptor 4 Signaling Pathway Signal Transduction By Phosphorylation Toll-like Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Cellular Response To Stress Response To Stress Apoptotic Process Programmed Cell Death Cell Death Death Regulation Of Innate Immune Response Cellular Response To Mechanical Stimulus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Activation Of MAPK Activity Immune Response-regulating Signaling Pathway Cellular Response To Lipopolysaccharide Cellular Response To Molecule Of Bacterial Origin Response To External Stimulus Response To Abiotic Stimulus Intracellular Signal Transduction Regulation Of Stress-activated MAPK Cascade Cellular Response To Organic Substance Cellular Response To Growth Factor Stimulus Regulation Of Cellular Protein Metabolic Process Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of MAP Kinase Activity Response To Growth Factor Response To Mechanical Stimulus Neurotrophin Signaling Pathway Regulation Of MAPK Cascade Fc-epsilon Receptor Signaling Pathway Organelle Disassembly Positive Regulation Of Immune Response Positive Regulation Of Signal Transduction
Tagcloud ?		afp antigen behavior bel biomarker colony contributes correlated cyclin depletion downregulated hcc hepatocellular immunohistochemistry interfering knockdown malignant marker mtt multiplicity overexpressed overexpression pattern poor relapse serves sirna sperm transfection