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WNT3A
Gene Name
wingless-type MMTV integration site family, member 3A
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Proteinaceous Extracellular Matrix
Extracellular Space
Endoplasmic Reticulum Lumen
Golgi Lumen
Plasma Membrane
Cell Surface
Early Endosome Membrane
Molecular Function
Transcription Coactivator Activity
Frizzled Binding
Frizzled-2 Binding
Protein Binding
Protein Domain Specific Binding
Receptor Agonist Activity
Biological Process
Osteoblast Differentiation
In Utero Embryonic Development
Positive Regulation Of Protein Phosphorylation
Heart Looping
Positive Regulation Of Receptor Internalization
Negative Regulation Of Heart Induction By Canonical Wnt Signaling Pathway
Axon Guidance
Positive Regulation Of Cell Proliferation
COP9 Signalosome Assembly
Negative Regulation Of Neuron Projection Development
Spinal Cord Association Neuron Differentiation
Hippocampus Development
Cell Proliferation In Forebrain
Wnt Signaling Pathway Involved In Forebrain Neuroblast Division
Dorsal/ventral Neural Tube Patterning
Hemopoiesis
Neuron Differentiation
Extracellular Matrix Organization
Mammary Gland Development
Positive Regulation Of B Cell Proliferation
Positive Regulation Of Protein Binding
Positive Regulation Of Peptidyl-serine Phosphorylation
Cellular Protein Localization
Positive Regulation Of Catenin Import Into Nucleus
Skeletal Muscle Cell Differentiation
Post-anal Tail Morphogenesis
Inner Ear Morphogenesis
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Negative Regulation Of Fat Cell Differentiation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Mesodermal Cell Fate Specification
Paraxial Mesodermal Cell Fate Commitment
Positive Regulation Of Collateral Sprouting In Absence Of Injury
Negative Regulation Of Axon Extension Involved In Axon Guidance
Negative Regulation Of Neurogenesis
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Palate Development
Canonical Wnt Signaling Pathway
Positive Regulation Of Protein Tyrosine Kinase Activity
Positive Regulation Of Dermatome Development
Canonical Wnt Signaling Pathway Involved In Cardiac Muscle Cell Fate Commitment
Regulation Of Microtubule Cytoskeleton Organization
Platelet Aggregation
Cellular Response To Retinoic Acid
Negative Regulation Of Canonical Wnt Signaling Pathway
Axis Elongation Involved In Somitogenesis
Positive Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin
Positive Regulation Of Canonical Wnt Signaling Pathway Involved In Controlling Type B Pancreatic Cell Proliferation
Positive Regulation Of Neural Precursor Cell Proliferation
Positive Regulation Of Cardiac Muscle Cell Differentiation
Pathways
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signaling by GPCR
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
negative regulation of TCF-dependent signaling by WNT ligand antagonists
Signaling by Wnt
GPCR ligand binding
Metabolic disorders of biological oxidation enzymes
WNT ligand biogenesis and trafficking
disassembly of the destruction complex and recruitment of AXIN to the membrane
WNT ligand secretion is abrogated by the PORCN inhibitor LGK974
TCF dependent signaling in response to WNT
regulation of FZD by ubiquitination
RNF mutants show enhanced WNT signaling and proliferation
XAV939 inhibits tankyrase, stabilizing AXIN
Signaling by WNT in cancer
Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS
Protein-protein Interactions
11 interactors:
DLG1
DLG2
DLG4
FZD1
GPC3
LRP1
LRP6
PORCN
RYK
WNT1
WNT2
Entrez ID
89780
HPRD ID
05897
Ensembl ID
ENSG00000154342
Uniprot IDs
P56704
PDB IDs
Enriched GO Terms of Interacting Partners
?
Wnt Signaling Pathway
Regulation Of Wnt Signaling Pathway
Receptor Localization To Synapse
Positive Regulation Of Wnt Signaling Pathway
Regulation Of Canonical Wnt Signaling Pathway
Cell-cell Signaling
Protein Localization To Synapse
Anatomical Structure Morphogenesis
Canonical Wnt Signaling Pathway
Neuron Differentiation
Signaling
Tissue Morphogenesis
Regulation Of Embryonic Development
Cell Communication
Regulation Of Signal Transduction
Positive Regulation Of Canonical Wnt Signaling Pathway
System Development
Regulation Of Signaling
Nervous System Development
Multicellular Organismal Development
Anatomical Structure Development
Negative Regulation Of Wnt Signaling Pathway
Generation Of Neurons
Receptor Clustering
Branching Morphogenesis Of An Epithelial Tube
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Neurogenesis
Nucleotide Phosphorylation
Organ Morphogenesis
Branching Involved In Ureteric Bud Morphogenesis
Hard Palate Development
Signal Transduction
Morphogenesis Of A Branching Epithelium
Epithelium Development
Ureteric Bud Morphogenesis
Negative Regulation Of Signal Transduction
Morphogenesis Of A Branching Structure
Developmental Process
Negative Regulation Of Signaling
Nephron Morphogenesis
Renal Tubule Morphogenesis
Regulation Of Epithelial Cell Proliferation
Regulation Of BMP Signaling Pathway
Stem Cell Proliferation
Positive Regulation Of Signal Transduction
Response To Stimulus
Tube Development
Cell Morphogenesis Involved In Differentiation
Renal Tubule Development
Cell Proliferation
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