IL18R1

Gene Name		interleukin 18 receptor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Receptor Activity Interleukin-1 Receptor Activity Protein Binding Interleukin-18 Receptor Activity
	Biological Process	Immune Response Signal Transduction Natural Killer Cell Activation Positive Regulation Of Interferon-gamma Production Interleukin-18-mediated Signaling Pathway Positive Regulation Of NF-kappaB Import Into Nucleus T-helper 1 Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Asthma ( 23028483 20860503 22561531) Atopic dermatitis ( 23042114) Celiac disease ( 20190752 18311140) Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233)
Protein-protein Interactions		4 interactors: CD48 IL18 IL1RAP IL37
Entrez ID		8809
HPRD ID		05138
Ensembl ID		ENSG00000115604
Uniprot IDs		B7ZKV7 Q13478
PDB IDs
Enriched GO Terms of Interacting Partners?		Interleukin-2 Biosynthetic Process Interleukin-2 Production Cytokine Biosynthetic Process Cytokine Metabolic Process Defense Response Inflammatory Response Immune System Process Granulocyte Macrophage Colony-stimulating Factor Biosynthetic Process Chemokine Biosynthetic Process Interleukin-13 Biosynthetic Process Cytokine Production Interferon-gamma Biosynthetic Process Response To Stress Positive Regulation Of NK T Cell Proliferation Immune Response Positive Regulation Of Natural Killer Cell Proliferation Regulation Of Natural Killer Cell Proliferation Chemokine Metabolic Process Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Production Chemokine Production Type 2 Immune Response Positive Regulation Of Interleukin-17 Production Cellular Response To Organic Substance Cytokine-mediated Signaling Pathway Positive Regulation Of Alpha-beta T Cell Proliferation Sleep Interferon-gamma Production Cellular Response To Cytokine Stimulus Positive Regulation Of NF-kappaB Import Into Nucleus Negative Regulation Of Myoblast Differentiation Positive Regulation Of Activated T Cell Proliferation Positive Regulation Of Natural Killer Cell Activation Response To Organic Substance T-helper 1 Type Immune Response Positive Regulation Of Tissue Remodeling Response To Cytokine Regulation Of Activated T Cell Proliferation Positive Regulation Of Transcription Factor Import Into Nucleus Lipopolysaccharide-mediated Signaling Pathway Regulation Of NF-kappaB Import Into Nucleus Regulation Of Myoblast Differentiation Negative Regulation Of Muscle Cell Differentiation Cell Surface Receptor Signaling Pathway Positive Regulation Of Interferon-gamma Production Natural Killer Cell Activation Regulation Of Tissue Remodeling Positive Regulation Of T Cell Proliferation Response To Stimulus Regulation Of Interferon-gamma Production Regulation Of Transcription Factor Import Into Nucleus
Tagcloud ?		affymetrix ancestry beyond ccr6 consortium crohn focusing genuine genuinely gwa harboring hits homologs humanhap550 il12 il12b il23 illumina reach replicated snp true trust tyk2 uncovered unleashing wellcome wtccc