TNFSF13

Gene Name		tumor necrosis factor (ligand) superfamily, member 13
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleoplasm Cytoplasm Cytosol External Side Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding
	Biological Process	Immunoglobulin Production In Mucosal Tissue Positive Regulation Of Germinal Center Formation Signal Transduction Positive Regulation Of Cell Proliferation Gene Expression Positive Regulation Of Isotype Switching To IgA Isotypes
Pathways		Regulation of mRNA stability by proteins that bind AU-rich elements HuR stabilizes mRNA
Drugs
Diseases
GWAS		IgA levels ( 22864923) IgA nephropathy ( 22197929) IgM levels ( 23118916) Non-albumin protein levels ( 22558069)
Protein-protein Interactions		10 interactors: CAMK1D FAS FURIN SDC2 TNFRSF11B TNFRSF13B TNFRSF14 TNFRSF17 TNFRSF1A TNFSF13B
Entrez ID		8741
HPRD ID		05128
Ensembl ID		ENSG00000161955
Uniprot IDs		B3KR02 O75888 Q2QBA2
PDB IDs
Enriched GO Terms of Interacting Partners?		Lymphocyte Homeostasis Leukocyte Homeostasis Signal Transduction Regulation Of Lymphocyte Activation Signaling Negative Regulation Of Lymphocyte Activation Cell Communication Response To Stimulus Regulation Of Cell Activation Negative Regulation Of Leukocyte Activation Cellular Response To Stimulus Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Immune System Process B Cell Homeostasis Negative Regulation Of B Cell Activation Homeostasis Of Number Of Cells Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Response To Organic Substance Regulation Of B Cell Proliferation Immunoglobulin Production Response To Organic Cyclic Compound Extracellular Matrix Organization Negative Regulation Of Lymphocyte Proliferation Negative Regulation Of Mononuclear Cell Proliferation Extracellular Structure Organization Cellular Response To Mechanical Stimulus Negative Regulation Of Immune System Process Negative Regulation Of Leukocyte Proliferation Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Negative Regulation Of Odontogenesis Of Dentin-containing Tooth T Cell Costimulation Response To External Stimulus Programmed Cell Death Positive Regulation Of Leukocyte Migration Cell Death Death Cell Surface Receptor Signaling Pathway Cellular Response To Tumor Necrosis Factor Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Dendrite Development Nerve Growth Factor Production Motor Neuron Apoptotic Process Response To Steroid Hormone Extrinsic Apoptotic Signaling Pathway Regulation Of Leukocyte Migration Immune System Process Regulation Of Cellular Process Positive Regulation Of Protein Metabolic Process Regulation Of Cytokine Production Response To Tumor Necrosis Factor
Tagcloud ?		aid april bcl2 bcl6 biased capabilities capture decisions deregulation discovered dlbcls ebf1 fusions guides igh immunoglobulin irf8 labor lymphomagenic lymphomas methodologies poised powerful prmd1 readily rearrangements translocations uncover viable