CAV2

Name	caveolin 2
Structure	No pdb structure
Novel Interactors	1 novel interactors: FOXP2
Interactors	13 interactors: CAV1 CSNK2A1 DNAJA1 DRD1 EGFR FLOT2 GOLGB1 MALL NCK1 RASA1 SDCBP SNCA SRC
GO Annotations	Cellular Component	Golgi Membrane Acrosomal Membrane Caveolar Macromolecular Signaling Complex Nucleus Cytoplasm Golgi Apparatus Plasma Membrane Caveola Focal Adhesion Membrane Transport Vesicle Cytoplasmic Vesicle Protein-containing Complex Plasma Membrane Raft Membrane Raft Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Protein Kinase Binding Protein-macromolecule Adaptor Activity D1 Dopamine Receptor Binding Heterotrimeric G-protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity Molecular Adaptor Activity Scaffold Protein Binding
	Biological Process	Endothelial Cell Proliferation Negative Regulation Of Endothelial Cell Proliferation Positive Regulation Of Endothelial Cell Proliferation Vesicle Fusion Mitochondrion Organization Endoplasmic Reticulum Organization Regulation Of Mitotic Nuclear Division Transforming Growth Factor Beta Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Cell Population Proliferation Insulin Receptor Signaling Pathway Skeletal Muscle Cell Proliferation Negative Regulation Of Skeletal Muscle Cell Proliferation Vesicle Organization Receptor-mediated Endocytosis Of Virus By Host Cell Viral Release From Host Cell Cell Differentiation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of MAPK Cascade Host-mediated Activation Of Viral Process Vesicle Docking Skeletal Muscle Fiber Development Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Dopamine Receptor Signaling Pathway Caveola Assembly Basement Membrane Organization
Pathways	Extra-nuclear estrogen signaling
GWAS	Antipsychotic drug-induced weight gain in schizophrenia ( 31447353 ) Atrial fibrillation ( 33990960 30061737 29892015 ) Glaucoma ( 31959993 30054594 ) Glaucoma (multi-trait analysis) ( 31959993 ) Glaucoma (primary open-angle) ( 20835238 33627673 29891935 25173105 ) Heart rate increase in response to exercise ( 29497042 ) Heart rate response to exercise ( 29769521 ) Heart rate response to recovery post exercise ( 29769521 ) Heart rate response to recovery post exercise (10 sec) ( 29497042 ) Heart rate response to recovery post exercise (20 sec) ( 29497042 ) Heart rate response to recovery post exercise (30 sec) ( 29497042 ) Heart rate response to recovery post exercise (40 sec) ( 29497042 ) Heart rate response to recovery post exercise (50 sec) ( 29497042 ) Intraocular pressure ( 30054594 31959993 25173106 31798171 28073927 29785010 29617998 ) P wave duration ( 28794112 ) Pancreatic ductal adenocarcinoma ( 33975060 ) PR interval ( 29127183 30046033 32439900 25035420 20062060 ) Refractive error ( 32231278 ) TPE interval (resting) ( 32386560 )
Entrez ID	858
HPRD ID	03029
Ensembl ID	ENSG00000105971
Uniprot IDs	P51636 Q53X57
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Membrane Raft Protein Sequestering Activity Regulation Of Intracellular Signal Transduction Regulation Of MAPK Cascade Regulation Of Primary Metabolic Process Regulation Of Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Macromolecule Metabolic Process Regulation Of Apoptotic Process Negative Regulation Of Protein Metabolic Process Regulation Of Cell Communication Regulation Of Signaling Negative Regulation Of Metabolic Process Protein Localization To Plasma Membrane Raft Negative Regulation Of Signaling Regulation Of Programmed Cell Death Negative Regulation Of Cell Communication Regulation Of Protein Metabolic Process Regulation Of Locomotion Perinuclear Region Of Cytoplasm Regulation Of Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Apoptotic Signaling Pathway Ephrin Receptor Signaling Pathway Enzyme Binding Positive Regulation Of Intracellular Signal Transduction Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Calcium Ion Transmembrane Transport Focal Adhesion Regulation Of Dopamine Uptake Involved In Synaptic Transmission Signal Complex Assembly Protein Localization To Membrane Raft Positive Regulation Of MAPK Cascade Caveola Substrate-dependent Cell Migration, Cell Extension Positive Regulation Of Cellular Component Biogenesis ATPase Binding Regulation Of RNA Metabolic Process Regulation Of Cellular Response To Stress Positive Regulation Of T Cell Activation Regulation Of Macromolecule Metabolic Process Negative Regulation Of Signal Transduction Positive Regulation Of Cell Migration Plasma Membrane Regulation Of Cell Migration Negative Regulation Of Transcription By RNA Polymerase II Cellular Response To Growth Factor Stimulus