SCIN

Description		scinderin
Image
GO Annotations	Cellular Component	Podosome Cytoplasm Cytoskeleton Brush Border Cell Cortex Actin Cytoskeleton Cell Projection Extracellular Exosome Anchoring Junction
	Molecular Function	Phosphatidylserine Binding Actin Binding Calcium Ion Binding Protein Binding 1-phosphatidylinositol Binding Phosphatidylinositol-4,5-bisphosphate Binding Metal Ion Binding Actin Filament Binding
	Biological Process	Central Nervous System Development Actin Polymerization Or Depolymerization Negative Regulation Of Cell Population Proliferation Calcium-ion Regulated Exocytosis Cell Projection Assembly Regulation Of Chondrocyte Differentiation Positive Regulation Of Apoptotic Process Actin Nucleation Positive Regulation Of Megakaryocyte Differentiation Actin Filament Severing Barbed-end Actin Filament Capping Positive Regulation Of Secretion Positive Regulation Of Actin Nucleation Actin Filament Capping
Pathways
Drugs
Diseases
GWAS		Height ( 31562340) Metabolite levels ( 23823483) Small cell lung carcinoma ( 28604730)
Novel Interacting Genes		1 novel interacting genes: UBAP2L
Interacting Genes		3 interacting genes: ACTA1 ACTC1 ACTG1
Entrez ID		85477
HPRD ID		11539
Ensembl ID		ENSG00000006747
Uniprot IDs		Q9Y6U3
PDB IDs		3FG6 5A1K 5A1M
Enriched GO Terms of Interacting Partners?		Actin Filament Skeletal Muscle Thin Filament Assembly Mesenchyme Migration Blood Microparticle Myosin Binding Actin Cytoskeleton Sarcomere Filopodium Cell Body Structural Constituent Of Cytoskeleton Basal Body Patch Actomyosin Structure Organization Lamellipodium Muscle Contraction Regulation Of Transepithelial Transport Muscle System Process Actin Filament Organization Positive Regulation Of Gene Expression Cytoplasmic Actin-based Contraction Involved In Cell Motility Protein Localization To Bicellular Tight Junction Dense Body Morphogenesis Of A Polarized Epithelium Membraneless Organelle Assembly Structural Constituent Of Postsynaptic Actin Cytoskeleton Positive Regulation Of Stress Granule Assembly ATP Binding Striated Muscle Thin Filament Cytoskeleton Extracellular Space Profilin Binding Actin Cytoskeleton Organization Regulation Of Stress Granule Assembly Hydrolase Activity Actin Filament-based Process Tissue Morphogenesis Focal Adhesion Cardiac Myofibril Assembly Nucleotide Binding Postsynaptic Actin Cytoskeleton Organization Actin-myosin Filament Sliding Protein Localization To Cell-cell Junction Calyx Of Held Supramolecular Fiber Organization Multicellular Organismal-level Homeostasis Postsynaptic Cytoskeleton Organization Heart Contraction Regulation Of Synaptic Vesicle Endocytosis Skeletal Muscle Fiber Development Extracellular Exosome Myofibril Assembly
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