SCIN

Gene Name		scinderin
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton Cell Cortex Protein Complex Extracellular Vesicular Exosome
	Molecular Function	Phosphatidylserine Binding Actin Binding Calcium Ion Binding 1-phosphatidylinositol Binding Phosphatidylinositol-4,5-bisphosphate Binding Actin Filament Binding
	Biological Process	Negative Regulation Of Cell Proliferation Calcium Ion-dependent Exocytosis Regulation Of Chondrocyte Differentiation Positive Regulation Of Apoptotic Process Actin Nucleation Positive Regulation Of Megakaryocyte Differentiation Actin Filament Severing Positive Regulation Of Secretion Actin Filament Capping
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: ACTA1 ACTC1 ACTG1
Entrez ID		85477
HPRD ID		11539
Ensembl ID		ENSG00000006747
Uniprot IDs		Q9Y6U3
PDB IDs		3FG6
Enriched GO Terms of Interacting Partners?		Myofibril Assembly Actomyosin Structure Organization Skeletal Muscle Thin Filament Assembly Striated Muscle Cell Development Skeletal Myofibril Assembly Muscle Cell Development Striated Muscle Cell Differentiation Muscle Cell Differentiation Muscle Filament Sliding Actin-myosin Filament Sliding Organelle Assembly Actin-mediated Cell Contraction Muscle Structure Development Actin Cytoskeleton Organization Actin Filament-based Movement Actin Filament-based Process Anatomical Structure Formation Involved In Morphogenesis Cytoskeleton Organization Skeletal Muscle Fiber Adaptation Muscle Contraction Movement Of Cell Or Subcellular Component Muscle System Process Muscle Organ Development Cell Development Actin Filament Organization Striated Muscle Tissue Development Cellular Component Assembly Muscle Tissue Development Anatomical Structure Morphogenesis Skeletal Muscle Adaptation Organelle Organization Cardiac Myofibril Assembly Skeletal Muscle Fiber Development Cell Differentiation Myotube Cell Development Response To Lithium Ion Platelet Aggregation System Development Muscle Fiber Development Sarcomere Organization Cardiac Muscle Contraction Cardiac Muscle Tissue Morphogenesis Myotube Differentiation Retina Homeostasis Muscle Tissue Morphogenesis Multicellular Organismal Development Heart Contraction Cardiac Muscle Cell Development Muscle Organ Morphogenesis Anatomical Structure Development
Tagcloud ?		a549 actin advantage arrest b1 capping carcinoma colony cytometry depletion excess g0 g1 h1299 homologue interference knockdown lentivirus lung p21 parp rnai scinderin severing silencing sub took yet zebrafish