TNKS1BP1

Description		tankyrase 1 binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Heterochromatin Nucleus Chromosome Cytoplasm Cytosol Cytoskeleton Adherens Junction CCR4-NOT Complex
	Molecular Function	Protein Binding Enzyme Binding Protein Serine/threonine Kinase Activator Activity Protein-containing Complex Binding Cadherin Binding Ankyrin Repeat Binding
	Biological Process	Nuclear-transcribed MRNA Poly(A) Tail Shortening Double-strand Break Repair Telomere Maintenance Via Telomerase Cellular Response To Ionizing Radiation
Pathways		Deadenylation of mRNA TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain M-decay: degradation of maternal mRNAs by maternally stored factors
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Hypertrophic cardiomyopathy (sarcomere positive) ( 33495597) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483)
Interacting Genes		3 interacting genes: CSNK2A1 TNKS TNKS2
Entrez ID		85456
HPRD ID		06164
Ensembl ID		ENSG00000149115
Uniprot IDs		A0A024R542 Q9C0C2
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Localization To Chromosome Positive Regulation Of Telomere Capping Negative Regulation Of DNA Metabolic Process Positive Regulation Of Wnt Signaling Pathway Protein Localization To Chromosome, Telomeric Region Protein Auto-ADP-ribosylation NAD+-protein-glutamate ADP-ribosyltransferase Activity NAD+-protein-aspartate ADP-ribosyltransferase Activity Regulation Of Telomere Capping Protein Poly-ADP-ribosylation Wnt Signaling Pathway NAD+-protein Mono-ADP-ribosyltransferase Activity Pericentriolar Material Positive Regulation Of Telomere Maintenance Via Telomerase Regulation Of Wnt Signaling Pathway Positive Regulation Of Telomere Maintenance Via Telomere Lengthening NAD+ Poly-ADP-ribosyltransferase Activity Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of DNA Biosynthetic Process Regulation Of DNA Metabolic Process Regulation Of Telomere Maintenance Via Telomere Lengthening Protein Localization To Organelle Positive Regulation Of Telomere Maintenance Negative Regulation Of Chromosome Organization Regulation Of DNA Biosynthetic Process Nucleotidyltransferase Activity Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Chromosome, Telomeric Region Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Telomeric Glycosyltransferase Activity Nuclear Envelope Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of Chromosome Organization Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Signal Transduction Negative Regulation Of Cell Cycle Process Membraneless Organelle Assembly Protein Polyubiquitination Positive Regulation Of DNA Metabolic Process Positive Regulation Of Aggrephagy Negative Regulation Of Sister Chromatid Cohesion Transferase Activity Positive Regulation Of Cell Communication Intracellular Protein Localization
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