APOL1

Gene Name		apolipoprotein L, 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Intrinsic Component Of Membrane Very-low-density Lipoprotein Particle High-density Lipoprotein Particle Blood Microparticle
	Molecular Function	Chloride Channel Activity Protein Binding Lipid Binding
	Biological Process	Chloride Transport Lipid Transport Receptor-mediated Endocytosis Cholesterol Metabolic Process Cytolysis Killing Of Cells Of Other Organism Lipoprotein Metabolic Process Innate Immune Response Chloride Transmembrane Transport
Pathways		Scavenging of heme from plasma
Drugs
Diseases
GWAS		Glomerulosclerosis ( 20668430)
Protein-protein Interactions		2 interactors: APOA1 CDC23
Entrez ID		8542
HPRD ID		04774
Ensembl ID		ENSG00000100342
Uniprot IDs		B1AH95 O14791 Q2KHQ6
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cell Adhesion Molecule Production Negative Regulation Of Interleukin-1 Beta Secretion Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling Cholesterol Import Negative Regulation Of Interleukin-1 Secretion High-density Lipoprotein Particle Clearance Protein Oxidation Positive Regulation Of Transferase Activity Negative Regulation Of Heterotypic Cell-cell Adhesion Negative Regulation Of Cytokine Secretion Involved In Immune Response High-density Lipoprotein Particle Assembly Metaphase/anaphase Transition Of Mitotic Cell Cycle Positive Regulation Of Triglyceride Catabolic Process Positive Regulation Of Cholesterol Esterification Regulation Of Intestinal Cholesterol Absorption Phospholipid Homeostasis Peptidyl-methionine Modification Regulation Of Cholesterol Esterification Peripheral Nervous System Axon Regeneration Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Exit From Mitosis Phospholipid Efflux Regulation Of Cytokine Secretion Involved In Immune Response Negative Regulation Of Catalytic Activity Positive Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Of Lipoprotein Lipase Activity Negative Regulation Of Interleukin-1 Beta Production Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway High-density Lipoprotein Particle Remodeling Glucocorticoid Metabolic Process Protein-lipid Complex Assembly Endothelial Cell Proliferation Reverse Cholesterol Transport Regulation Of Organelle Organization Negative Chemotaxis Negative Regulation Of Lipase Activity Protein K11-linked Ubiquitination Regulation Of Interleukin-1 Beta Secretion Phosphatidylcholine Biosynthetic Process Positive Regulation Of Lipid Catabolic Process Plasma Lipoprotein Particle Remodeling Positive Regulation Of Steroid Metabolic Process Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Mitotic Metaphase Plate Congression Cholesterol Efflux Regulation Of Cdc42 Protein Signal Transduction Positive Regulation Of Fatty Acid Metabolic Process Metaphase Plate Congression Blood Vessel Endothelial Cell Migration Regulation Of Substrate Adhesion-dependent Cell Spreading
Tagcloud ?		advance americans apolipoprotein august collapsing doi elevate glomerulosclerosis hairpin identifies illustrates inducers injurious interferon interferons irf1 irf2 irf3 online polyi publication relied segmental stat2 tbk1 tlr tlr3 toll upregulating