RHPN2

Gene Name		rhophilin, Rho GTPase binding protein 2
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function
	Biological Process	Signal Transduction
Pathways
Drugs
Diseases
GWAS		Colorectal cancer ( 19011631) Obesity-related traits ( 23251661)
Protein-protein Interactions		6 interactors: KRT18 RARG RHOA RHOB SMURF1 TGFBR1
Entrez ID		85415
HPRD ID		10192
Ensembl ID		ENSG00000131941
Uniprot IDs		Q8IUC4
PDB IDs		2VSV
Enriched GO Terms of Interacting Partners?		Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Negative Regulation Of Chondrocyte Differentiation Cellular Response To Organic Substance Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cartilage Development Anatomical Structure Morphogenesis Response To Organic Substance Anatomical Structure Development Rho Protein Signal Transduction Regulation Of Chondrocyte Differentiation Signal Transduction Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cell Cycle Developmental Process Signaling Regulation Of Apoptotic Process Regulation Of Cartilage Development Cell Communication Cell Surface Receptor Signaling Pathway Positive Regulation Of Protein Import Into Nucleus Regulation Of Cell Death Skeletal System Development Golgi To Plasma Membrane CFTR Protein Transport Cellular Response To Growth Factor Stimulus Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cytokinesis Wound Healing Response To Growth Factor Negative Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Cell Differentiation Positive Regulation Of Cell Death Tissue Development Cell Activation Cell Development Cytoplasmic Transport Response To Wounding Cellular Response To Stimulus Growth Plate Cartilage Chondrocyte Growth Cell Morphogenesis Involved In Differentiation Negative Regulation Of Cell Differentiation Positive Regulation Of Intracellular Protein Transport Growth Plate Cartilage Chondrocyte Development Harderian Gland Development
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