RGS8

Gene Name		regulator of G-protein signaling 8
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Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane
	Molecular Function	GTPase Activator Activity
	Biological Process	Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity
Pathways		Signaling by GPCR GPCR downstream signaling G alpha (i) signalling events
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: ADRB2 GOLGA2
Entrez ID		85397
HPRD ID		06221
Ensembl ID		ENSG00000135824
Uniprot IDs		P57771
PDB IDs		2IHD 2ODE
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Binding Negative Regulation Of Binding Regulation Of Protein Binding Regulation Of Binding Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Vasodilation By Norepinephrine-epinephrine Involved In Regulation Of Systemic Arterial Blood Pressure Heat Generation Diet Induced Thermogenesis Activation Of Transmembrane Receptor Protein Tyrosine Kinase Activity Negative Regulation Of Smooth Muscle Contraction Adrenergic Receptor Signaling Pathway Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Response To Dietary Excess Negative Regulation Of Multicellular Organism Growth Negative Regulation Of Muscle Contraction Negative Regulation Of Systemic Arterial Blood Pressure Temperature Homeostasis Activation Of Adenylate Cyclase Activity Endosome To Lysosome Transport Vasodilation Bone Resorption Positive Regulation Of Adenylate Cyclase Activity Positive Regulation Of Bone Mineralization Positive Regulation Of Biomineral Tissue Development Brown Fat Cell Differentiation Lysosomal Transport Regulation Of Vasodilation Positive Regulation Of Lyase Activity Negative Regulation Of Blood Pressure Regulation Of Smooth Muscle Contraction Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Regulation Of Adenylate Cyclase Activity Response To Cold Bone Remodeling Positive Regulation Of CAMP Biosynthetic Process Regulation Of Cyclase Activity Regulation Of Sodium Ion Transport Positive Regulation Of CAMP Metabolic Process Regulation Of Bone Mineralization Regulation Of Blood Vessel Size Regulation Of Tube Size Vacuolar Transport Positive Regulation Of Cyclic Nucleotide Metabolic Process Negative Regulation Of Developmental Growth Regulation Of CAMP Biosynthetic Process Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Ossification Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of Multicellular Organism Growth Regulation Of CAMP Metabolic Process
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