ALG10

Gene Name		ALG10, alpha-1,2-glucosyltransferase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Transferase Activity, Transferring Hexosyl Groups
	Biological Process	Dolichol-linked Oligosaccharide Biosynthetic Process Protein N-linked Glycosylation Via Asparagine Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Defective ALG2 causes ALG2-CDG (CDG-1i) Diseases of glycosylation Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Defective ALG1 causes ALG1-CDG (CDG-1k) Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective MOGS causes MOGS-CDG (CDG-2b) Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Defective ALG11 causes ALG11-CDG (CDG-1p) Diseases associated with N-glycosylation of proteins
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: KCNH1 KCNH2
Entrez ID		84920
HPRD ID		10346
Ensembl ID
Uniprot IDs		Q5BKT4
PDB IDs
Enriched GO Terms of Interacting Partners?		Peptidyl-histidine Phosphorylation Phosphorelay Signal Transduction System Potassium Ion Transmembrane Transport Negative Regulation Of Potassium Ion Export Potassium Ion Transport Regulation Of Membrane Potential Signal Transduction By Phosphorylation Regulation Of Heart Rate By Hormone Regulation Of Ion Transmembrane Transport Synaptic Transmission Regulation Of Ion Transport Regulation Of Heart Rate By Chemical Signal Monovalent Inorganic Cation Transport Membrane Repolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Potassium Ion Export Membrane Repolarization Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Negative Regulation Of Potassium Ion Transmembrane Transport Potassium Ion Homeostasis Metal Ion Transport Positive Regulation Of Potassium Ion Transmembrane Transport Cell-cell Signaling Cation Transmembrane Transport Peptidyl-amino Acid Modification Ventricular Cardiac Muscle Cell Action Potential Myoblast Fusion Negative Regulation Of Potassium Ion Transport Regulation Of Membrane Repolarization Regulation Of Heart Rate By Cardiac Conduction Cardiac Muscle Cell Action Potential Involved In Contraction Positive Regulation Of Potassium Ion Transport Cation Transport Syncytium Formation Membrane Depolarization During Action Potential Cardiac Muscle Cell Action Potential Ion Transmembrane Transport Protein Phosphorylation Regulation Of Potassium Ion Transmembrane Transport Regulation Of Cardiac Muscle Cell Contraction Cardiac Conduction Negative Regulation Of Ion Transmembrane Transport Cardiac Muscle Contraction Negative Regulation Of Transmembrane Transport Cellular Response To Drug Myotube Differentiation Regulation Of Potassium Ion Transport Heart Contraction Transmembrane Transport Ion Transport
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