AIFM2

Description		AIF family member 2
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GO Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Mitochondrion Mitochondrial Outer Membrane Lipid Droplet Cytosol Plasma Membrane Membrane Mitochondrial Membrane
	Molecular Function	DNA Binding Electron-transferring-flavoprotein Dehydrogenase Activity Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor Flavin Adenine Dinucleotide Binding
	Biological Process	Ubiquinone Metabolic Process Apoptotic Mitochondrial Changes Respiratory Electron Transport Chain Vitamin K Metabolic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Ferroptosis Regulation Of Cellular Response To Oxidative Stress Cellular Detoxification
Pathways		TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
Drugs
Diseases
GWAS		Post bronchodilator FEV1/FVC ratio ( 26634245) Rheumatoid arthritis ( 30891314)
Interacting Genes		3 interacting genes: CNPY4 PLXNB2 TRIM21
Entrez ID		84883
HPRD ID		09797
Ensembl ID		ENSG00000042286
Uniprot IDs		Q9BRQ8
PDB IDs		8JSC 8WIK 8YO8 8YOQ 8YOX
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Deubiquitination Stress Granule Disassembly Positive Regulation Of Protein Binding Negative Regulation Of Protein Deubiquitination TRNA Stabilization Excitatory Synapse Assembly Negative Regulation Of Translation In Response To Stress Positive Regulation Of Viral Entry Into Host Cell Suppression Of Viral Release By Host Protein K27-linked Ubiquitination Negative Regulation Of Viral Transcription Semaphorin Receptor Activity Semaphorin Receptor Complex Regulation Of Viral Transcription Negative Regulation Of Protein Metabolic Process Regulation Of Viral Entry Into Host Cell Regulation Of Translation In Response To Stress
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