ORAI1

Gene Name		ORAI calcium release-activated calcium modulator 1
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Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Membrane Protein Complex
	Molecular Function	Protein Binding Calmodulin Binding Store-operated Calcium Channel Activity Identical Protein Binding
	Biological Process	Store-operated Calcium Entry Immune System Process Blood Coagulation Regulation Of Calcium Ion Transport Positive Regulation Of Calcium Ion Transport Calcium Ion Transmembrane Transport
Pathways		Signaling by the B Cell Receptor (BCR) Platelet homeostasis Elevation of cytosolic Ca2+ levels Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Platelet calcium homeostasis Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: TRPC3 TRPC6
Entrez ID		84876
HPRD ID		08599
Ensembl ID
Uniprot IDs		Q96D31
PDB IDs		4EHQ
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Calcium Ion Transport Regulation Of Calcium Ion Transport Platelet Activation Positive Regulation Of Ion Transport Calcium Ion Transmembrane Transport Calcium Ion Transport Axon Guidance Blood Coagulation Hemostasis Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Response To Inorganic Substance Axonogenesis Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Axon Development Regulation Of Body Fluid Levels Cell Morphogenesis Involved In Neuron Differentiation Wound Healing Chemotaxis Regulation Of Ion Transport Neuron Projection Morphogenesis Cell Activation Response To Wounding Cell Morphogenesis Involved In Differentiation Positive Regulation Of Transport Neuron Projection Development Metal Ion Transport Cell Projection Morphogenesis Cell Part Morphogenesis Positive Regulation Of Cardiac Muscle Hypertrophy Cation Transmembrane Transport Neuron Development Cell Morphogenesis Response To Abiotic Stimulus Response To ATP Neuron Differentiation Cell Projection Organization Regulation Of Cardiac Muscle Hypertrophy Cation Transport Locomotion Ion Transmembrane Transport Positive Regulation Of Calcium Ion Transport Into Cytosol Movement Of Cell Or Subcellular Component Positive Regulation Of Ion Transmembrane Transporter Activity Generation Of Neurons Positive Regulation Of Transporter Activity Cellular Response To Hydrogen Peroxide Neurogenesis Transmembrane Transport Ion Transport Cell Development
Tagcloud ?		acinar agonist agonists carboxyl clustering coexpression depleted diminished dispersed glands hek intensities junctions mildly muscarinic nfat operated pm polybasic puncta recruits salivary soce stim1 stim1deltak stim2 stimulus store stores