KLHL22

Gene Name		kelch-like family member 22
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Centrosome Polar Microtubule Cul3-RING Ubiquitin Ligase Complex Mitotic Spindle
	Molecular Function	Protein Binding
	Biological Process	Mitotic Sister Chromatid Segregation Protein Monoubiquitination Mitotic Spindle Assembly Checkpoint Cell Division
Pathways
Drugs
Diseases
GWAS		Retinopathy in non-diabetics ( 23393555)
Protein-protein Interactions		1 interactors: PLK1
Entrez ID		84861
HPRD ID		07858
Ensembl ID		ENSG00000099910
Uniprot IDs		Q53GT1
PDB IDs
Enriched GO Terms of Interacting Partners?		Activation Of APC-Cdc20 Complex Activity Polar Body Extrusion After Meiotic Divisions Activation Of Anaphase-promoting Complex Activity Meiotic Cytokinesis Positive Regulation Of Mitotic Metaphase/anaphase Transition Metaphase/anaphase Transition Of Mitotic Cell Cycle Protein Localization To Chromatin Positive Regulation Of Chromosome Segregation Positive Regulation Of Peptidyl-threonine Phosphorylation Protein Destabilization Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Localization To Chromosome G2 DNA Damage Checkpoint Mitotic Spindle Assembly Checkpoint Mitotic Nuclear Envelope Disassembly Female Meiotic Division Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Positive Regulation Of Mitotic Nuclear Division Negative Regulation Of Chromosome Segregation Nuclear Envelope Disassembly Mitotic Cytokinesis Microtubule Bundle Formation Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Response To Antibiotic Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Proteasomal Protein Catabolic Process Nuclear Envelope Organization Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Ligase Activity Mitotic Sister Chromatid Segregation Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Sister Chromatid Segregation Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Chromosome Organization Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Centrosome Organization
Tagcloud ?