PSRC1

Gene Name		proline/serine-rich coiled-coil 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Nucleoplasm Cytoplasm Spindle Cytosol Spindle Microtubule Microtubule Cytoskeleton Midbody
	Molecular Function	Protein Binding Microtubule Binding
	Biological Process	Microtubule Bundle Formation Mitotic Metaphase Plate Congression Negative Regulation Of Cell Growth Positive Regulation Of Microtubule Polymerization Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Transcription, DNA-templated Cell Division Regulation Of Mitotic Spindle Organization
Pathways
Drugs
Diseases
GWAS		Cholesterol, total ( 20686565) Coronary heart disease ( 17634449 21378988) LDL cholesterol ( 18262040 18179892 18193043 18193044 19060906 19060910 20686565) Lipid metabolism phenotypes ( 19936222) Lipoprotein-associated phospholipase A2 activity and mass ( 20442857) Metabolite levels ( 21909109) Myocardial infarction (early onset) ( 19198609) Progranulin levels ( 21087763) Response to statin therapy ( 20339536)
Protein-protein Interactions		2 interactors: APP SRGN
Entrez ID		84722
HPRD ID		13127
Ensembl ID		ENSG00000134222
Uniprot IDs		A8K0M8 Q6PGN9
PDB IDs
Enriched GO Terms of Interacting Partners?		Platelet Degranulation Platelet Activation Maintenance Of Granzyme B Location In T Cell Secretory Granule T Cell Secretory Granule Organization Maintenance Of Protease Location In Mast Cell Secretory Granule Synaptic Growth At Neuromuscular Junction Mast Cell Secretory Granule Organization Exocytosis Collateral Sprouting In Absence Of Injury Blood Coagulation Hemostasis Collateral Sprouting Axon Midline Choice Point Recognition Granzyme-mediated Apoptotic Signaling Pathway Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Secretion By Cell Axon Choice Point Recognition Regulation Of Body Fluid Levels Wound Healing Secretion Neuron Remodeling Cell Activation Response To Wounding Cellular Copper Ion Homeostasis Apoptotic Process Negative Regulation Of Bone Mineralization Negative Regulation Of Biomineral Tissue Development Copper Ion Homeostasis Suckling Behavior Programmed Cell Death Cell Death Death Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Cytokine Secretion RNA Polyadenylation Neuron Recognition Secretory Granule Organization Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Vesicle-mediated Transport Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development
Tagcloud ?		ags aurka aurkb bop1 bub1 bub1b ccna2 ccnb1 ccne2 cdc20 cdc25b cdc25c cdk5 cdkn1a cenpe deoxyribonucleotides earliest foxm1 illumina impdh inosine kegg mcm2 monophosphate mpa mycophenolic rrm1 segregation transcriptomic