CASQ2

Gene Name		calsequestrin 2 (cardiac muscle)
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Gene Ontology Annotations	Cellular Component	Intracellular Cytoplasm Voltage-gated Calcium Channel Complex Junctional Sarcoplasmic Reticulum Membrane Sarcoplasmic Reticulum Z Disc Junctional Membrane Complex Sarcoplasmic Reticulum Membrane Sarcoplasmic Reticulum Lumen Calcium Channel Complex
	Molecular Function	Calcium Ion Binding Protein Binding Protein Homodimerization Activity Calcium-dependent Protein Binding
	Biological Process	Regulation Of Heart Rate Detection Of Calcium Ion Striated Muscle Contraction Regulation Of Cell Communication By Electrical Coupling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Ion Transmembrane Transport Negative Regulation Of Potassium Ion Transport Sarcomere Organization Sequestering Of Calcium Ion Protein Polymerization Transmembrane Transport Cardiac Muscle Contraction Regulation Of Membrane Repolarization Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cellular Response To Caffeine Purkinje Myocyte To Ventricular Cardiac Muscle Cell Signaling Negative Regulation Of Potassium Ion Transmembrane Transporter Activity
Pathways		Ion channel transport Stimuli-sensing channels
Drugs
Diseases
GWAS		Ventricular conduction ( 21076409)
Protein-protein Interactions		4 interactors: ANKRD1 CSNK2A1 CSNK2A2 TRDN
Entrez ID		845
HPRD ID		00256
Ensembl ID		ENSG00000118729
Uniprot IDs		B4DEF0 B4DIB0 O14958
PDB IDs		2VAF
Enriched GO Terms of Interacting Partners?		Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Negative Regulation Of Chromosome Organization Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Nuclear Division Positive Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Checkpoint Endoplasmic Reticulum Membrane Organization Regulation Of Proteasomal Protein Catabolic Process Regulation Of Chromosome Organization Cell Differentiation Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Striated Muscle Cell Differentiation Regulation Of Cell Cycle Phase Transition Cell Cycle Checkpoint Regulation Of Cell Division Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Cell Communication By Electrical Coupling Wnt Signaling Pathway Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Muscle Cell Differentiation Generation Of Neurons Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Proteolysis Neurogenesis Response To Muscle Stretch Regulation Of Cardiac Muscle Cell Membrane Potential Negative Regulation Of Calcium Ion Transport Into Cytosol Negative Regulation Of Protein Processing Regulation Of Protein Catabolic Process Axon Guidance Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Sarcoplasmic Reticulum Calcium Ion Transport Regulation Of Protein Processing Cell Development Response To External Stimulus Regulation Of Mitotic Cell Cycle
Tagcloud ?		3d aligned alphamhc averaged cardiomyocyte cd172a cms contractile ctnt cvs dissociated ec50 embryoid esc fibrin hes2 hesc inotropy isoproterenol monolayers nn patch patches purity sarcomeres serca2 sirpa uniformly velocities