MAML2

Gene Name		mastermind-like 2 (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Golgi Apparatus Nuclear Speck
	Molecular Function	Transcription Coactivator Activity
	Biological Process	Transcription Initiation From RNA Polymerase II Promoter Notch Signaling Pathway Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Signaling by NOTCH1 HD Domain Mutants in Cancer Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Signaling by NOTCH NOTCH2 intracellular domain regulates transcription Notch-HLH transcription pathway Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant NOTCH1 Intracellular Domain Regulates Transcription Signaling by NOTCH2 Generic Transcription Pathway Pre-NOTCH Transcription and Translation Signaling by NOTCH1 Pre-NOTCH Expression and Processing Signaling by NOTCH1 PEST Domain Mutants in Cancer Signaling by NOTCH1 in Cancer Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Constitutive Signaling by NOTCH1 PEST Domain Mutants FBXW7 Mutants and NOTCH1 in Cancer
Drugs
Diseases
GWAS		Corneal astigmatism ( 23322567) Height ( 23456168) Response to treatment for acute lymphoblastic leukemia ( 19176441) Ulcerative colitis ( 23128233) Waist-to-hip circumference ratio (interaction) ( 23192594)
Protein-protein Interactions		6 interactors: CREBBP DIABLO NOTCH1 NOTCH2 NOTCH3 NOTCH4
Entrez ID		84441
HPRD ID		09608
Ensembl ID
Uniprot IDs		Q8IZL2
PDB IDs
Enriched GO Terms of Interacting Partners?		Notch Receptor Processing Notch Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Negative Regulation Of Cell Differentiation Cell Fate Commitment Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription Of Notch Receptor Target Interleukin-4 Secretion Notch Signaling Involved In Heart Development Pulmonary Valve Morphogenesis Interleukin-4 Production Blood Vessel Development Vasculature Development Stem Cell Maintenance Cell Surface Receptor Signaling Pathway Embryonic Limb Morphogenesis Regulation Of Cell Differentiation Limb Morphogenesis Regulation Of Endothelial Cell Differentiation Limb Development Glomerulus Vasculature Development Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Stem Cell Development Cardiovascular System Development Cardiac Atrium Morphogenesis Inflammatory Response To Antigenic Stimulus Cytokine Secretion Heart Valve Morphogenesis Heart Valve Development Positive Regulation Of BMP Signaling Pathway Stem Cell Differentiation Transcription, DNA-templated Angiogenesis RNA Biosynthetic Process Anatomical Structure Morphogenesis Cell Fate Determination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Embryo Development Regulation Of DNA-templated Transcription In Response To Stress Cardiac Septum Morphogenesis Glomerulus Development Morphogenesis Of An Epithelial Sheet Blood Vessel Morphogenesis Signal Transduction Embryonic Digit Morphogenesis Pattern Specification Process Endothelial Cell Differentiation Protein Metabolic Process Neuron Fate Commitment
Tagcloud ?		breakpoint call combines comparisons complexity computational discordance frame fusions inversion libraries mate nasopharyngeal npc pair ptk2 ptplb reads rearrangements reconstruction recurrently rsrc1 sanger smash somatic sp3 split structural yap1