NSMAF

Description		neutral sphingomyelinase activation associated factor
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane
	Molecular Function	Protein Binding
	Biological Process	Ceramide Metabolic Process Signal Transduction Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Amide Metabolic Process Positive Regulation Of Lipid Metabolic Process Regulation Of Membrane Lipid Metabolic Process
Pathways		TNFR1-mediated ceramide production
Drugs
Diseases
GWAS		Basophil count ( 32888494) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Systolic blood pressure and diastolic blood pressure (bivariate analysis) ( 33539483)
Interacting Genes		6 interacting genes: ACTB CD40 DCP1A DCP1B RACK1 TNFRSF1A
Entrez ID		8439
HPRD ID		09117
Ensembl ID		ENSG00000035681
Uniprot IDs		Q92636
PDB IDs
Enriched GO Terms of Interacting Partners?		Enzyme Activator Activity Deadenylation-independent Decapping Of Nuclear-transcribed MRNA 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] Hydrolase Activity Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA MRNA Methylguanosine-cap Decapping RNA Decapping Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Kinesin Binding Positive Regulation Of DNA Recombination Cytoplasmic Ribonucleoprotein Granule Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Cellular Response To Mechanical Stimulus Cell Surface Receptor Signaling Pathway Via STAT Cell Surface Receptor Signaling Pathway Via JAK-STAT Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Regulation Of Protein Localization To Plasma Membrane Regulation Of Macromolecule Biosynthetic Process Regulation Of Multicellular Organismal Development Positive Regulation Of Developmental Process Regulation Of Gene Expression Regulation Of Norepinephrine Uptake Positive Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Process IRE1-RACK1-PP2A Complex Negative Regulation Of Translational Frameshifting P-body Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Regulation Of DNA Recombination Regulation Of Macromolecule Metabolic Process Transporter Regulator Activity Positive Regulation Of Interleukin-4-mediated Signaling Pathway Positive Regulation Of Protein Kinase C Signaling Response To Cobalamin Regulation Of Protein Localization To Cell Periphery Regulation Of Transepithelial Transport Cellular Response To Erythropoietin Negative Regulation Of Extracellular Matrix Constituent Secretion Pulmonary Valve Development Tumor Necrosis Factor Receptor Superfamily Complex Regulation Of Protein Localization To Membrane Protein Localization To Adherens Junction Regulation Of Metabolic Process Dense Body Regulation Of Protein Kinase C Signaling Response To Erythropoietin Regulation Of Cytokine-mediated Signaling Pathway Negative Regulation Of Translational Elongation
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