SPNS1

Gene Name		spinster homolog 1 (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Inner Membrane Lysosomal Membrane Integral Component Of Membrane Vesicle
	Molecular Function	Protein Binding Sphingolipid Transporter Activity
	Biological Process	Sphingosine-1-phosphate Signaling Pathway Lipid Transport Locomotion Transmembrane Transport
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: BCL2 BCL2L1
Entrez ID		83985
HPRD ID		11599
Ensembl ID		ENSG00000169682
Uniprot IDs		H3BMF4 Q9H2V7
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Anoikis Regulation Of Anoikis Release Of Cytochrome C From Mitochondria Regulation Of Mitochondrial Membrane Potential Negative Regulation Of Autophagy Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Response To Gamma Radiation Neuron Apoptotic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Mitochondrial Membrane Organization Neuron Death Ovarian Follicle Development Apoptotic Mitochondrial Changes Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Mitochondrion Organization Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Ovulation Cycle Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway Regulation Of Autophagy Female Gonad Development Ovulation Cycle Development Of Primary Female Sexual Characteristics Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Response To Ionizing Radiation Response To Alkaloid Mitochondrial Transport Male Gonad Development Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Neuron Apoptotic Process Intrinsic Apoptotic Signaling Pathway Male Sex Differentiation Intracellular Receptor Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Neuron Death Negative Regulation Of Retinal Cell Programmed Cell Death Negative Regulation Of Cellular PH Reduction CD8-positive, Alpha-beta T Cell Lineage Commitment Apoptotic Process In Bone Marrow Negative Regulation Of Mitotic Cell Cycle Gonad Development Development Of Primary Sexual Characteristics Regulation Of Neuron Apoptotic Process Germ Cell Development Negative Regulation Of Apoptotic Signaling Pathway
Tagcloud ?		acidification ameliorates autolysosomal autolysosome autophagic autophagosome autophagy beclin biogenesis blockage carbohydrate counteract defect deficit exacerbates hallmarks irrespective lysosomal lysosome operates rescue senescence spin spinster suppressing suppressors unexpectedly vacuolar vertebrates