NANOG

Gene Name		Nanog homeobox
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus
	Molecular Function	Enhancer Sequence-specific DNA Binding DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Mesodermal Cell Fate Commitment Endodermal Cell Fate Specification Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Proliferation Positive Regulation Of Cell Proliferation Gonad Development Embryonic Pattern Specification Negative Regulation Of Cell Fate Commitment Regulation Of Gene Expression Stem Cell Division Stem Cell Maintenance Cell Differentiation Negative Regulation Of BMP Signaling Pathway Response To Retinoic Acid Somatic Stem Cell Maintenance Regulation Of Cell Differentiation Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Transcriptional regulation of pluripotent stem cells POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: MED12 PRKCE RHOXF2
Entrez ID		79923
HPRD ID		06397
Ensembl ID		ENSG00000111704
Uniprot IDs		Q9H9S0
PDB IDs		2KT0
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Glucuronidation TRAM-dependent Toll-like Receptor 4 Signaling Pathway Axis Elongation Involved In Somitogenesis Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Negative Regulation Of Sodium Ion Transmembrane Transport Cellular Response To Ethanol Positive Regulation Of Fibroblast Migration Macrophage Activation Involved In Immune Response Locomotory Exploration Behavior Negative Regulation Of Sodium Ion Transport Positive Regulation Of Synaptic Transmission, GABAergic
Tagcloud ?		abcc3 abcc5 abcg2 aldh1 astrocytoma ckit dige enforcing exhibiting gbm gbms glioblastoma klf4 lna locked maldi multiforme nefl nestin neurofilament nucleic onco sensitized sox2 stemness temozolomide tmz tof u251