NHEJ1

Gene Name		nonhomologous end-joining factor 1
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Gene Ontology Annotations	Cellular Component	Nucleus Nonhomologous End Joining Complex
	Molecular Function	DNA Binding Protein Binding
	Biological Process	Double-strand Break Repair Via Nonhomologous End Joining DNA Recombination Central Nervous System Development Response To Ionizing Radiation B Cell Differentiation T Cell Differentiation Positive Regulation Of Ligase Activity
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: LIG4 XRCC4
Entrez ID		79840
HPRD ID		07784
Ensembl ID		ENSG00000187736
Uniprot IDs		Q9H9Q4
PDB IDs		2QM4 2R9A 3Q4F 3RWR 3SR2 3W03
Enriched GO Terms of Interacting Partners?		Pro-B Cell Differentiation Establishment Of Integrated Proviral Latency Establishment Of Viral Latency Immunoglobulin V(D)J Recombination DNA Ligation Involved In DNA Repair Lymphoid Progenitor Cell Differentiation DNA Ligation Cellular Response To Lithium Ion Double-strand Break Repair Via Nonhomologous End Joining Isotype Switching V(D)J Recombination Response To Lithium Ion Response To X-ray Somatic Recombination Of Immunoglobulin Gene Segments Somatic Diversification Of Immunoglobulins Immunoglobulin Production Involved In Immunoglobulin Mediated Immune Response B Cell Activation Involved In Immune Response Response To Gamma Radiation Immunoglobulin Production Positive Regulation Of Fibroblast Proliferation T Cell Differentiation In Thymus Regulation Of Fibroblast Proliferation Cellular Response To Metal Ion Cellular Response To Inorganic Substance Response To Ionizing Radiation Double-strand Break Repair Hematopoietic Progenitor Cell Differentiation T Cell Differentiation Leukocyte Activation Involved In Immune Response B Cell Activation Negative Regulation Of Neuron Apoptotic Process Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Negative Regulation Of Neuron Death DNA Ligation Involved In DNA Recombination DNA Recombination Lymphocyte Differentiation Regulation Of Neuron Apoptotic Process Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Leukocyte Mediated Immunity Adaptive Immune Response T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Regulation Of Neuron Death Leukocyte Cell-cell Adhesion Response To Metal Ion Homotypic Cell-cell Adhesion Leukocyte Differentiation
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