TFPI2

Gene Name		tissue factor pathway inhibitor 2
Image
Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix Nucleus
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Extracellular Matrix Structural Constituent
	Biological Process	Blood Coagulation Negative Regulation Of Endopeptidase Activity
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: F11 KLKB1 PLG SKIL SMURF2
Entrez ID		7980
HPRD ID		08962
Ensembl ID		ENSG00000105825
Uniprot IDs		P48307 Q8NAK6
PDB IDs		1ZR0
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Fibrinolysis Regulation Of Fibrinolysis Negative Regulation Of Blood Coagulation Negative Regulation Of Coagulation Negative Regulation Of Wound Healing Regulation Of Blood Coagulation Plasminogen Activation Regulation Of Wound Healing Blood Coagulation, Intrinsic Pathway Fibrinolysis Blood Coagulation Hemostasis Proteolysis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Body Fluid Levels Wound Healing Extracellular Matrix Disassembly Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Zymogen Activation Response To Wounding Transforming Growth Factor Beta Receptor Signaling Pathway Factor XII Activation Protein Activation Cascade Transcription Initiation From RNA Polymerase II Promoter Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Mononuclear Cell Migration Response To Transforming Growth Factor Beta Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin DNA-templated Transcription, Initiation Protein Processing Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Ubiquitin-dependent SMAD Protein Catabolic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Plasma Kallikrein-kinin Cascade Negative Regulation Of Fibrinolysis Extracellular Matrix Organization Extracellular Structure Organization Protein Heterotrimerization Protein Homotrimerization Trophoblast Giant Cell Differentiation Positive Regulation Of Protein Processing Muscle Structure Development In Utero Embryonic Development Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Response To Stimulus Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process
Tagcloud ?		anticipated aplp2 appi bikunin canonical cleavage cleave cleaved cocrystal conformation displaying hai2 hepatocyte kunitz mesotrypsin offers p1 polypeptide possessing preferences protease proteolytic selectin stabilization stabilized substrates tfpi1 trypsin uniquely