TFPI2

Description		tissue factor pathway inhibitor 2
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Matrix
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Extracellular Matrix Structural Constituent Peptidase Inhibitor Activity
	Biological Process	Blood Coagulation Hemostasis
Pathways		Developmental Lineage of Pancreatic Ductal Cells
Drugs
Diseases
GWAS		Heart rate response to recovery post exercise (10 sec) ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heart rate response to recovery post exercise (30 sec) ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042)
Novel Interacting Genes		1 novel interacting genes: ZAN
Interacting Genes		5 interacting genes: F11 KLKB1 PLG SKIL SMURF2
Entrez ID		7980
HPRD ID		08962
Ensembl ID		ENSG00000105825
Uniprot IDs		P48307
PDB IDs		1ZR0
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Fibrinolysis Regulation Of Fibrinolysis Negative Regulation Of Blood Coagulation Negative Regulation Of Hemostasis Negative Regulation Of Coagulation Negative Regulation Of Wound Healing Regulation Of Hemostasis Regulation Of Blood Coagulation Coagulation Blood Coagulation Hemostasis Plasminogen Activation Serine-type Peptidase Activity Regulation Of Wound Healing Serine-type Endopeptidase Activity Fibrinolysis Regulation Of Response To Wounding Protein Processing Zymogen Activation Regulation Of Body Fluid Levels Protein Maturation SMAD Binding Negative Regulation Of BMP Signaling Pathway Proteolysis Peptidase Activity Serine-type Aminopeptidase Activity Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of BMP Signaling Pathway Extracellular Space Factor XII Activation Regulation Of Multicellular Organismal Process Negative Regulation Of Cellular Response To Growth Factor Stimulus Trans-synaptic Signaling By BDNF, Modulating Synaptic Transmission Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Trans-synaptic Signaling By BDNF Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Trophoblast Cell Migration Protein Domain Specific Binding Protein Antigen Binding Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Negative Regulation Of Fibrinolysis Trans-synaptic Signaling, Modulating Synaptic Transmission Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Trophoblast Giant Cell Differentiation Lens Fiber Cell Differentiation Negative Regulation Of Multicellular Organismal Process Regulation Of Cellular Response To Growth Factor Stimulus Plasma Membrane
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