ALG9

Gene Name		ALG9, alpha-1,2-mannosyltransferase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Mannosyltransferase Activity Dol-P-Man:Man(8)GlcNAc(2)-PP-Dol Alpha-1,2-mannosyltransferase Activity Dol-P-Man:Man(6)GlcNAc(2)-PP-Dol Alpha-1,2-mannosyltransferase Activity
	Biological Process	Dolichol-linked Oligosaccharide Biosynthetic Process Protein N-linked Glycosylation Via Asparagine Post-translational Protein Modification Cellular Protein Metabolic Process Mannosylation
Pathways		Defective ALG2 causes ALG2-CDG (CDG-1i) Diseases of glycosylation Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Defective ALG1 causes ALG1-CDG (CDG-1k) Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective MOGS causes MOGS-CDG (CDG-2b) Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Defective ALG11 causes ALG11-CDG (CDG-1p) Diseases associated with N-glycosylation of proteins
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: BHMT H2AFX
Entrez ID		79796
HPRD ID		09504
Ensembl ID
Uniprot IDs		Q9H6U8
PDB IDs
Enriched GO Terms of Interacting Partners?		S-methylmethionine Cycle S-methylmethionine Metabolic Process Amino-acid Betaine Catabolic Process Regulation Of Homocysteine Metabolic Process L-methionine Salvage Methionine Biosynthetic Process Amino-acid Betaine Metabolic Process Methionine Metabolic Process Sulfur Amino Acid Biosynthetic Process Positive Regulation Of DNA Repair Sulfur Amino Acid Metabolic Process Regulation Of DNA Repair Positive Regulation Of Response To DNA Damage Stimulus Double-strand Break Repair Via Homologous Recombination Recombinational Repair Nucleosome Assembly Regulation Of Response To DNA Damage Stimulus Cellular Amino Acid Biosynthetic Process Chromatin Assembly Nucleosome Organization Response To Ionizing Radiation Positive Regulation Of DNA Metabolic Process Double-strand Break Repair Chromatin Assembly Or Disassembly DNA Damage Checkpoint Protein-DNA Complex Assembly Protein Methylation DNA Packaging
Tagcloud ?		adbrk2 arntl dpysl2 drd3 dusp6 famine gad1 gch1 gnaz grin1 grin2b gsk3b hip1r homoeostasis hspa5 impa2 kcnq2 per3 pik3c3 pip5k2a plcg1 rgs4 shuts slc6a3 slc6a4 sybl1 synj1 timeless wfs1