FBXO31

Description		F-box protein 31
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GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Cytoskeleton SCF Ubiquitin Ligase Complex Neuronal Cell Body
	Molecular Function	Protein Binding Cyclin Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	DNA Damage Response Protein Ubiquitination DNA Damage Response, Signal Transduction By P53 Class Mediator Anaphase-promoting Complex-dependent Catabolic Process SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic G1 DNA Damage Checkpoint Signaling Cellular Response To Oxidative Stress P38MAPK Cascade Signal Transduction In Response To DNA Damage Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Experiencing mood swings ( 29500382) Feeling nervous ( 29500382) Major depressive disorder ( 22472876) Neurociticism ( 29500382) Neuroticism ( 29255261)
Interacting Genes		5 interacting genes: AKT1 CCND1 CDT1 GHR MDM2
Entrez ID		79791
HPRD ID		10954
Ensembl ID		ENSG00000103264
Uniprot IDs		A0A0C4DGU8 Q5XUX0
PDB IDs		5VZT 5VZU
Enriched GO Terms of Interacting Partners?		Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Response To Alcohol Positive Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Response To Nutrient Levels Positive Regulation Of Mitotic Cell Cycle Response To UV-A Regulation Of G1/S Transition Of Mitotic Cell Cycle Response To UV Response To Hormone Response To Growth Hormone Response To Magnesium Ion Cellular Response To Peptide Hormone Stimulus Proline-rich Region Binding Regulation Of Cell Cycle G1/S Phase Transition Response To Ether Regulation Of Cell Cycle Process Response To Ketone Negative Regulation Of Protein Maturation Response To Steroid Hormone Response To Lipid Response To Food Positive Regulation Of Cell Cycle Process Response To Iron Ion Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Cell Population Proliferation Response To Peptide Hormone Response To Metal Ion Response To Light Stimulus Positive Regulation Of Cell Cycle Regulation Of Cell Cycle Cellular Response To Hormone Stimulus Regulation Of Mitotic Cell Cycle Phase Transition Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Enzyme Binding Regulation Of Protein Maturation Response To Estrogen Transcription Repressor Complex Endoplasmic Reticulum Unfolded Protein Response Response To Radiation Positive Regulation Of Developmental Process Protein Kinase Binding Response To Vitamin Proteasomal Protein Catabolic Process Animal Organ Development Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Mitotic Cell Cycle Positive Regulation Of Smooth Muscle Cell Proliferation
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