CARS2

Description		cysteinyl-tRNA synthetase 2, mitochondrial
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion
	Molecular Function	Nucleotide Binding Aminoacyl-tRNA Ligase Activity Cysteine-tRNA Ligase Activity ATP Binding Ligase Activity Metal Ion Binding
	Biological Process	Translation TRNA Aminoacylation For Protein Translation Cysteinyl-tRNA Aminoacylation
Pathways		Mitochondrial tRNA aminoacylation
Drugs		Cysteine
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Diastolic blood pressure ( 26969751) Parkinson's disease ( 34064523)
Interacting Genes		7 interacting genes: GABARAP GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B OGT RIPK4
Entrez ID		79587
HPRD ID		07763
Ensembl ID		ENSG00000134905
Uniprot IDs		B7Z7E6 Q9HA77
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Mitophagy Autophagy Of Mitochondrion Macroautophagy Autophagosome Maturation Autophagosome Membrane Autophagosome Cellular Response To Nutrient Levels Autophagosome Assembly Autophagosome Organization Autophagy Phospholipid Binding Protein-containing Complex Disassembly Vacuole Organization Cellular Response To Starvation Response To Nutrient Levels Response To Starvation GABA Receptor Binding Organelle Assembly Ubiquitin Protein Ligase Binding Beta-tubulin Binding Microtubule Binding Protein-containing Complex Organization Microtubule Cytoplasmic Vesicle Catabolic Process Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Cellular Component Assembly Regulation Of Protein Localization To Synapse Regulation Of Proteasomal Protein Catabolic Process Regulation Of Receptor Localization To Synapse Organelle Organization Regulation Of Rac Protein Signal Transduction Cellular Response To Stress Endomembrane System Organelle Membrane Response To Stress Negative Regulation Of Proteasomal Protein Catabolic Process Cytosol Regulation Of Protein Catabolic Process Regulation Of Proteolysis Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Protein Catabolic Process Axoneme Protein O-acetylglucosaminyltransferase Activity Positive Regulation Of Protein K48-linked Ubiquitination Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
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