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MAPKAP1
Gene Name
mitogen-activated protein kinase associated protein 1
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Cytosol
Plasma Membrane
Cytoplasmic Membrane-bounded Vesicle
Molecular Function
Protein Binding
Phosphatidylinositol-4,5-bisphosphate Binding
Phosphatidylinositol-3,4,5-trisphosphate Binding
Ras GTPase Binding
Protein Kinase Binding
Phosphatidylinositol-3,4-bisphosphate Binding
Phosphatidic Acid Binding
Phosphatidylinositol-3,5-bisphosphate Binding
Biological Process
Epidermal Growth Factor Receptor Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
Substantia Nigra Development
T Cell Costimulation
Fc-epsilon Receptor Signaling Pathway
Innate Immune Response
Negative Regulation Of Ras Protein Signal Transduction
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Phosphatidylinositol-mediated Signaling
Pathways
Signaling by the B Cell Receptor (BCR)
Signaling by FGFR in disease
Costimulation by the CD28 family
PIP3 activates AKT signaling
Signaling by EGFRvIII in Cancer
VEGFA-VEGFR2 Pathway
Signaling by SCF-KIT
Downstream signaling events of B Cell Receptor (BCR)
DAP12 signaling
PI3K/AKT activation
PI-3K cascade
PI3K events in ERBB2 signaling
VEGFR2 mediated vascular permeability
Downstream signaling of activated FGFR
Innate Immune System
Signaling by PDGF
Signalling by NGF
DAP12 interactions
GAB1 signalosome
CD28 co-stimulation
CD28 dependent PI3K/Akt signaling
Signaling by Ligand-Responsive EGFR Variants in Cancer
NGF signalling via TRKA from the plasma membrane
Signaling by ERBB4
Signaling by Overexpressed Wild-Type EGFR in Cancer
Role of LAT2/NTAL/LAB on calcium mobilization
Constitutive PI3K/AKT Signaling in Cancer
PI3K events in ERBB4 signaling
Signaling by FGFR
Signaling by ERBB2
Signaling by EGFR
Signaling by VEGF
Downstream signal transduction
Fc epsilon receptor (FCERI) signaling
Signaling by EGFR in Cancer
PI3K/AKT Signaling in Cancer
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions
8 interactors:
ABCB1
AKT1S1
CDC42EP1
ECI1
EIF4EBP1
MAPK8
PRR5L
YWHAG
Entrez ID
79109
HPRD ID
17464
Ensembl ID
ENSG00000119487
Uniprot IDs
Q9BPZ7
PDB IDs
3VOQ
Enriched GO Terms of Interacting Partners
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Intracellular Signal Transduction
TOR Signaling
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Negative Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Protein Phosphorylation
Positive Regulation Of Mitochondrion Organization
Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Phosphorylation
Positive Regulation Of Organelle Organization
Regulation Of Protein Metabolic Process
Regulation Of Mitochondrion Organization
TORC2 Signaling
G2/M Transition Of Mitotic Cell Cycle
Regulation Of Signal Transduction
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Mitotic Cell Cycle Process
Regulation Of Signaling
Mitotic Cell Cycle
IRES-dependent Translational Initiation
Cap-independent Translational Initiation
JUN Phosphorylation
Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Apoptotic Signaling Pathway
Xenobiotic Transport
Positive Regulation Of Deacetylase Activity
Cellular Response To Organic Substance
Signal Transduction
Neurotrophin TRK Receptor Signaling Pathway
Cellular Response To Insulin Stimulus
Negative Regulation Of Protein Kinase Activity
Regulation Of Cellular Component Organization
Neurotrophin Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Positive Regulation Of Determination Of Dorsal Identity
Enzyme Linked Receptor Protein Signaling Pathway
Negative Regulation Of Kinase Activity
Positive Regulation Of Intracellular Transport
Regulation Of Organelle Organization
Signaling
Negative Regulation Of Cellular Metabolic Process
Response To Stimulus
Cytoplasmic Translational Initiation
Fc Receptor Signaling Pathway
Cell Communication
Cell Cycle Process
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