MLPH

Gene Name		melanophilin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Microtubule Organizing Center Dendrite Cortical Actin Cytoskeleton Microtubule Plus-end Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Actin Binding Rab GTPase Binding Myosin V Binding Metal Ion Binding Microtubule Plus-end Binding
	Biological Process	Protein Targeting Melanocyte Differentiation Melanosome Localization
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 21743057)
Protein-protein Interactions		3 interactors: MYO5A RAB27A RAB27B
Entrez ID		79083
HPRD ID		09409
Ensembl ID		ENSG00000115648
Uniprot IDs		B3KSS2 G5E9G5 Q9BV36
PDB IDs
Enriched GO Terms of Interacting Partners?		Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Cellular Pigmentation Multivesicular Body Sorting Pathway Pigmentation Protein Secretion Establishment Of Vesicle Localization Vesicle Localization Establishment Of Organelle Localization Exocytosis Organelle Localization Melanocyte Differentiation Neuroepithelial Cell Differentiation Secretion By Cell Rab Protein Signal Transduction Developmental Pigmentation Positive Regulation Of Exocytosis Vesicle Docking Involved In Exocytosis Secretion Vesicle Docking Membrane Docking Positive Regulation Of Constitutive Secretory Pathway Complement-dependent Cytotoxicity Regulation Of Exocytosis Cellular Protein Localization Protein Transport Vesicle-mediated Transport Multivesicular Body Organization Cytotoxic T Cell Degranulation Establishment Of Protein Localization Ras Protein Signal Transduction Intracellular Transport Endoplasmic Reticulum Localization Vesicle Transport Along Actin Filament Exosomal Secretion Protein Localization Positive Regulation Of Secretion Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Establishment Of Localization In Cell Natural Killer Cell Degranulation Regulation Of Vesicle-mediated Transport Locomotion Involved In Locomotory Behavior Endomembrane System Organization Secretory Granule Localization T Cell Mediated Cytotoxicity Cellular Localization Epithelial Cell Differentiation Synaptic Transmission
Tagcloud ?		blue breeds californian castor checkered coat colour colours cosegregation dilute diluted eumelanic fairy frameshift grey griscelli indel lod marburg melanophilin pearly pheomelanic pigmentation pigmentations rab27a rex segregating sib vienna