CA6

Name	carbonic anhydrase 6
Structure
Novel Interactors	3 novel interactors: MTOR SDHB SLC45A1
Interactors	4 interactors: FCGRT KRT31 KRT40 NOTCH2NLA
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Carbonate Dehydratase Activity Zinc Ion Binding Lyase Activity Metal Ion Binding
	Biological Process	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste
Pathways	Reversible hydration of carbon dioxide
Drugs	Benzthiazide Cyclothiazide Zonisamide Mafenide Ellagic acid
GWAS	Blood protein levels ( 30072576 ) Post bronchodilator FEV1 ( 26634245 )
Entrez ID	765
HPRD ID	00264
Ensembl ID	ENSG00000131686
Uniprot IDs	B4DUH8 P23280
PDB IDs	3FE4
GO Terms Enriched among Interactors ?	IgG Immunoglobulin Transcytosis In Epithelial Cells Mediated By FcRn Immunoglobulin Receptor Regulation Of Locomotor Rhythm TFIIIC-class Transcription Factor Complex Binding Positive Regulation Of SCF-dependent Proteasomal Ubiquitin-dependent Catabolic Process Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization 3 Iron, 4 Sulfur Cluster Binding Sucrose Transport D-glucose:proton Symporter Activity Sucrose:proton Symporter Activity Galactose:proton Symporter Activity Immunoglobulin Transcytosis In Epithelial Cells Positive Regulation Of Pentose-phosphate Shunt Inositol Hexakisphosphate Binding RNA Polymerase III Type 1 Promoter Sequence-specific DNA Binding RNA Polymerase III Type 2 Promoter Sequence-specific DNA Binding Negative Regulation Of TORC2 Signaling Negative Regulation Of Lysosome Organization T-helper 1 Cell Lineage Commitment Respiratory Chain Complex II (succinate Dehydrogenase) Succinate Dehydrogenase (quinone) Activity Galactose Transmembrane Transport Positive Regulation Of Cytoplasmic Translational Initiation TORC1 Complex Energy Derivation By Oxidation Of Organic Compounds Regulation Of Pentose-phosphate Shunt Cellular Response To Methionine Voluntary Musculoskeletal Movement 'de Novo' Pyrimidine Nucleobase Biosynthetic Process RNA Polymerase III Type 3 Promoter Sequence-specific DNA Binding Positive Regulation Of Wound Healing, Spreading Of Epidermal Cells Intermediate Filament Structural Molecule Activity Mitochondrial Electron Transport, Succinate To Ubiquinone Ubiquinone Binding Response To Methionine Succinate Metabolic Process Beta-2-microglobulin Binding Regulation Of NADP Metabolic Process Pyrimidine Nucleobase Biosynthetic Process Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I TORC2 Complex Negative Regulation Of Cell Size Vascular Endothelial Cell Response To Laminar Fluid Shear Stress