ZIC2

Gene Name		Zic family member 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Chromatin DNA Binding Metal Ion Binding
	Biological Process	Neural Tube Closure Transcription, DNA-templated Brain Development Visual Perception Retinal Ganglion Cell Axon Guidance Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Developmental Pigmentation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Pathways
Drugs
Diseases
GWAS		Refractive error ( 23396134)
Protein-protein Interactions		3 interactors: GLI1 GLI2 GLI3
Entrez ID		7546
HPRD ID		04353
Ensembl ID		ENSG00000043355
Uniprot IDs		O95409
PDB IDs
Enriched GO Terms of Interacting Partners?		Proximal/distal Pattern Formation Notochord Regression Positive Regulation Of Neural Precursor Cell Proliferation Digestive Tract Morphogenesis Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification Smoothened Signaling Pathway Involved In Ventral Spinal Cord Interneuron Specification Smoothened Signaling Pathway Involved In Regulation Of Cerebellar Granule Cell Precursor Cell Proliferation Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning Ventral Midline Development Regulation Of Smoothened Signaling Pathway Regulation Of Neural Precursor Cell Proliferation Smoothened Signaling Pathway Cerebellar Purkinje Cell-granule Cell Precursor Cell Signaling Involved In Regulation Of Granule Cell Precursor Cell Proliferation Dorsal/ventral Pattern Formation Digestive Tract Development Digestive System Development Positive Regulation Of Cerebellar Granule Cell Precursor Proliferation Hindgut Morphogenesis Notochord Morphogenesis Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Hindgut Development Ventral Spinal Cord Interneuron Specification Spinal Cord Motor Neuron Cell Fate Specification Lung Development Anatomical Structure Regression Ventral Spinal Cord Interneuron Fate Commitment Respiratory Tube Development Ventral Spinal Cord Interneuron Differentiation Respiratory System Development Notochord Development Embryonic Organ Morphogenesis Spinal Cord Dorsal/ventral Patterning Neuron Fate Specification Spinal Cord Patterning Tube Morphogenesis Dorsal/ventral Neural Tube Patterning Forebrain Development Cerebellar Cortex Morphogenesis Pattern Specification Process Embryonic Digestive Tract Development Embryonic Organ Development Gland Development Spinal Cord Motor Neuron Differentiation Organ Formation Epithelial Cell Differentiation Cerebellum Morphogenesis Hindbrain Morphogenesis Pituitary Gland Development Ventral Spinal Cord Development Neural Tube Patterning
Tagcloud ?		alobar anteverted bitemporal c1091 consanguineous etiologically fissures frank gli2 gln364leufs holoprosencephaly hpe insipidus insufficiencies mlu mosm nares narrowing neuroanatomic osmolality osmolarity palpebral philtrum prosencephalon sonic syndromic teratogenic trh upslanting