VLDLR

Gene Name		very low density lipoprotein receptor
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Gene Ontology Annotations	Cellular Component	Plasma Membrane Coated Pit Membrane Integral Component Of Membrane Very-low-density Lipoprotein Particle Receptor Complex
	Molecular Function	Glycoprotein Binding Low-density Lipoprotein Receptor Activity Calcium Ion Binding Protein Binding Very-low-density Lipoprotein Particle Receptor Activity Apolipoprotein Binding Very-low-density Lipoprotein Particle Binding Glycoprotein Transporter Activity Reelin Receptor Activity Calcium-dependent Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Lipid Transport Receptor-mediated Endocytosis Signal Transduction Nervous System Development Memory Cholesterol Metabolic Process Ventral Spinal Cord Development Glycoprotein Transport Very-low-density Lipoprotein Particle Clearance Reelin-mediated Signaling Pathway Positive Regulation Of Protein Kinase Activity Positive Regulation Of Dendrite Development
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease (age of onset) ( 22005931) Gambling ( 22780124) Vascular endothelial growth factor levels ( 21757650)
Protein-protein Interactions		9 interactors: APOE CD36 CLU DAB1 LPL LRPAP1 MYLIP RELN SNX17
Entrez ID		7436
HPRD ID		01895
Ensembl ID		ENSG00000147852
Uniprot IDs		P98155 Q5VVF5
PDB IDs		1V9U 3DPR
Enriched GO Terms of Interacting Partners?		Regulation Of Beta-amyloid Clearance Positive Regulation Of Neurofibrillary Tangle Assembly Lateral Motor Column Neuron Migration Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Spinal Cord Motor Neuron Migration Regulation Of Plasma Lipoprotein Particle Levels Regulation Of Tau-protein Kinase Activity N-methyl-D-aspartate Receptor Clustering Cholesterol Transport Sterol Transport Positive Regulation Of Protein Metabolic Process Positive Regulation Of Inclusion Body Assembly Very-low-density Lipoprotein Particle Remodeling Positive Regulation Of Beta-amyloid Formation Triglyceride-rich Lipoprotein Particle Remodeling Receptor-mediated Endocytosis CGMP-mediated Signaling Cholesterol Catabolic Process Negative Regulation Of Beta-amyloid Formation Positive Regulation Of Cell Differentiation Lipid Homeostasis Positive Regulation Of Cholesterol Storage Negative Regulation Of Amyloid Precursor Protein Catabolic Process Nitric Oxide Mediated Signal Transduction Regulation Of Beta-amyloid Formation Regulation Of Protein Phosphorylation Regulation Of Cellular Component Organization Regulation Of Inclusion Body Assembly Reverse Cholesterol Transport Regulation Of Amyloid Precursor Protein Catabolic Process Triglyceride Catabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Steroid Catabolic Process Positive Regulation Of Macrophage Derived Foam Cell Differentiation Acylglycerol Catabolic Process Glial Cell Differentiation Plasma Lipoprotein Particle Remodeling Regulation Of Protein Metabolic Process Positive Regulation Of Dendritic Spine Development Lipid Metabolic Process Positive Regulation Of Lipid Storage Postsynaptic Membrane Organization Regulation Of Phosphorylation Plasma Lipoprotein Particle Clearance Cyclic-nucleotide-mediated Signaling Positive Regulation Of Protein Catabolic Process Endocytosis Cellular Localization Gliogenesis
Tagcloud ?		1alpha ag basel chip display elucidated endothelial enhancement hampered hif huvecs hypoxia immunoblot karger luciferase markedly mimicked pretreated pretreatment protection protects recruitment robust sala salvianolic suppressing umbilical vein