UGP2

Name	UDP-glucose pyrophosphorylase 2
Structure
Interactors	8 interactors: ABCA1 ARIH2 CBS GLRX3 PCBP1 PLEKHF2 TTN UBC
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	UTP:glucose-1-phosphate Uridylyltransferase Activity Protein Binding D-glucose Binding Transferase Activity Nucleotidyltransferase Activity Pyrimidine Ribonucleotide Binding Identical Protein Binding Metal Ion Binding UTP-monosaccharide-1-phosphate Uridylyltransferase Activity Uridylyltransferase Activity
	Biological Process	Glycogen Metabolic Process Glycogen Biosynthetic Process UDP-alpha-D-glucose Metabolic Process UDP-glucuronate Biosynthetic Process Brain Development Energy Derivation By Oxidation Of Organic Compounds Glucose 1-phosphate Metabolic Process
Pathways	Formation of the active cofactor, UDP-glucuronate Glycogen synthesis
GWAS	Clozapine-induced agranulocytosis ( 25187353 ) Smoking initiation (ever regular vs never regular) ( 30679032 ) Systolic blood pressure ( 26969751 )
Entrez ID	7360
HPRD ID	08934
Ensembl ID	ENSG00000169764
Uniprot IDs	A0A140VKE1 Q16851
PDB IDs	3R2W 3R3I 4R7P
GO Terms Enriched among Interactors ?	Response To Vitamin B3 Apolipoprotein A-I-mediated Signaling Pathway Floppase Activity Regulation Of High-density Lipoprotein Particle Assembly Sphingolipid Translocation Positive Regulation Of High-density Lipoprotein Particle Assembly Apolipoprotein A-I Receptor Activity Response To Vitamin Response To Nutrient Apolipoprotein A-I Binding Phosphatidylserine Floppase Activity Sphingolipid Floppase Activity Cysteine Biosynthetic Process Cysteine Biosynthetic Process From Serine L-serine Catabolic Process Transsulfuration Cysteine Biosynthetic Process Via Cystathionine Homocysteine Catabolic Process Hydrogen Sulfide Biosynthetic Process Nitrite Reductase (NO-forming) Activity Cerebellum Morphogenesis Hydrogen Sulfide Metabolic Process L-cysteine Catabolic Process Cystathionine Beta-synthase Activity Nitric Oxide Binding Carbon Monoxide Binding Sequence-specific Single Stranded DNA Binding Titin-telethonin Complex Structural Molecule Activity Conferring Elasticity Myosin Filament Assembly Skeletal Muscle Myosin Thick Filament Assembly Sarcomerogenesis Z Disc Lipoprotein Biosynthetic Process Phosphatidylcholine Floppase Activity Skeletal Muscle Thin Filament Assembly DNA Protection Modified Amino Acid Binding Viral RNA Genome Replication Detection Of Muscle Stretch Telethonin Binding