TBXT

Description		T-box transcription factor T
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Mesoderm Formation Cell Fate Specification Somitogenesis Heart Morphogenesis Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Signal Transduction Mesoderm Development Anterior/posterior Axis Specification, Embryo Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Cardiac Muscle Cell Myoblast Differentiation Primitive Streak Formation
Pathways		Cardiogenesis Germ layer formation at gastrulation Epithelial-Mesenchymal Transition (EMT) during gastrulation Formation of paraxial mesoderm Formation of axial mesoderm Formation of definitive endoderm
Drugs
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: RPS6KA2
Interacting Genes		3 interacting genes: NFIA NFIB NFIC
Entrez ID		6862
HPRD ID		03236
Ensembl ID		ENSG00000164458
Uniprot IDs		J3KP65 O15178
PDB IDs		5QRF 5QRG 5QRH 5QRI 5QRJ 5QRK 5QRL 5QRM 5QRN 5QRO 5QRP 5QRQ 5QRR 5QRS 5QRT 5QRU 5QRV 5QRW 5QRX 5QRY 5QRZ 5QS0 5QS1 5QS2 5QS3 5QS4 5QS5 5QS6 5QS7 5QS8 5QS9 5QSA 5QSB 5QSC 5QSD 5QSE 5QSF 5QSG 5QSH 5QSI 5QSJ 5QSK 5QSL 5QT0 6F58 6F59 6ZU8 7HI8 7HI9 7ZK2 7ZKF 7ZL2 8A10 8A7N 8CDN 8FMU
Enriched GO Terms of Interacting Partners?		Glial Cell Fate Specification DNA Replication Exit From Mitosis Generation Of Neurons Neuron Fate Specification Glial Cell Proliferation DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Retina Development In Camera-type Eye Cell Fate Specification DNA-binding Transcription Factor Activity Neural Precursor Cell Proliferation Negative Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Lung Ciliated Cell Differentiation Neurogenesis DNA Metabolic Process Double-stranded DNA Binding Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Macromolecule Biosynthetic Process Cell Differentiation Involved In Salivary Gland Development Fibrillar Center Negative Regulation Of Mesenchymal Cell Proliferation Involved In Lung Development Brain Renin-angiotensin System Positive Regulation Of Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Principal Sensory Nucleus Of Trigeminal Nerve Development Developmental Maturation Chromatin Response To Wounding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Club Cell Differentiation Positive Regulation Of Macromolecule Metabolic Process Salivary Gland Cavitation Anterior Commissure Morphogenesis Ribosomal Protein S6 Kinase Activity Regulation Of Blood Volume By Renin-angiotensin Positive Regulation Of Transcription By RNA Polymerase II Ureter Development Positive Regulation Of Metabolic Process Gene Expression Multi-ciliated Epithelial Cell Differentiation Type II Pneumocyte Differentiation Cerebellar Mossy Fiber Negative Regulation Of Mesenchymal Cell Proliferation Nervous System Process Involved In Regulation Of Systemic Arterial Blood Pressure Animal Organ Development Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Type I Pneumocyte Differentiation Negative Regulation Of Meiotic Nuclear Division Macromolecule Biosynthetic Process
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