SSR4

Description		signal sequence receptor subunit 4
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GO Annotations	Cellular Component	Endoplasmic Reticulum Sec61 Translocon Complex Endoplasmic Reticulum Membrane Endomembrane System Membrane Extracellular Exosome
	Molecular Function
	Biological Process
Pathways		SRP-dependent cotranslational protein targeting to membrane
Drugs
Diseases
GWAS
Novel Interacting Genes		2 novel interacting genes: PPP1R16B TAFAZZIN
Interacting Genes		5 interacting genes: HECW1 NLGN3 POMP PTEN SSR3
Entrez ID		6748
HPRD ID		02101
Ensembl ID		ENSG00000180879
Uniprot IDs		P51571
PDB IDs		8B6L
Enriched GO Terms of Interacting Partners?		Rhythmic Synaptic Transmission Presynaptic Membrane Organization Presynaptic Membrane Assembly Positive Regulation Of Excitatory Postsynaptic Potential Social Behavior Membrane Assembly Modulation Of Excitatory Postsynaptic Potential Negative Regulation Of Synaptic Vesicle Clustering Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Synapse Assembly Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Positive Regulation Of Cardiolipin Metabolic Process Regulation Of Nervous System Process Central Nervous System Myelin Maintenance Symmetric, GABA-ergic, Inhibitory Synapse Regulation Of Plasma Membrane Bounded Cell Projection Organization Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Regulation Of Cell Projection Organization Adult Behavior Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Phosphatidylinositol Phosphate Phosphatase Activity Membrane Organization Regulation Of Cardiolipin Metabolic Process Cardiolipin Acyl-chain Remodeling Asymmetric, Glutamatergic, Excitatory Synapse Locomotor Rhythm Regulation Of Cell Junction Assembly Cognition Cell Junction Assembly Chemical Synaptic Transmission Phosphatidylinositol-3-phosphate Phosphatase Activity Cellular Response To Electrical Stimulus Learning Or Memory Ubiquitin Ligase Activator Activity Spindle Assembly Involved In Female Meiosis Negative Regulation Of Peptidyl-serine Phosphorylation Regulation Of Synaptic Vesicle Clustering Glycerolipid Metabolic Process Postsynaptic Specialization Assembly Prepulse Inhibition Neuron-neuron Synaptic Transmission Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Anatomical Structure Morphogenesis Meiotic Spindle Assembly Synapse Maturation Negative Regulation Of Cell Size Maternal Behavior
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