SRM

Description		spermidine synthase
Image
GO Annotations	Cellular Component	Cytosol
	Molecular Function	Catalytic Activity Spermidine Synthase Activity Protein Binding Transferase Activity Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Polyamine Metabolic Process Polyamine Biosynthetic Process Spermidine Biosynthetic Process Cellular Response To Leukemia Inhibitory Factor
Pathways		Metabolism of polyamines
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 34315874) Aspartate aminotransferase levels ( 34315874) Beard thickness ( 26926045)
Novel Interacting Genes		2 novel interacting genes: ASXL1 TNFRSF14
Interacting Genes		4 interacting genes: CDC42 CEBPA SOX12 TERF1
Entrez ID		6723
HPRD ID		01692
Ensembl ID		ENSG00000116649
Uniprot IDs		P19623
PDB IDs		2O05 2O06 2O07 2O0L 3RW9
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell Adhesion Macrophage Differentiation GBD Domain Binding Storage Vacuole RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 Positive Regulation Of Cell Activation C/EBP Complex Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Positive Regulation Of Shelterin Complex Assembly Negative Regulation Of Adaptive Immune Memory Response Endothelin Receptor Signaling Pathway Involved In Heart Process Myeloid Leukocyte Differentiation Positive Regulation Of Macromolecule Metabolic Process Regulation Of Fat Cell Differentiation CHOP-C/EBP Complex Regulation Of Cell Activation Apolipoprotein A-I Receptor Binding Neuropilin Signaling Pathway White Fat Cell Proliferation PR-DUB Complex Positive Regulation Of Metabolic Process Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Pinocytosis G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Regulation Of Cell Adhesion Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Response To Phenylpropanoid Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Establishment Of Protein Localization To Chromosome Regulation Of Establishment Of Protein Localization To Telomere Telomerase Activity Shelterin Complex Ankyrin Repeat Binding Lung Saccule Development Bone Marrow Development Regulation Of Kidney Size Negative Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Establishment Of Golgi Localization Spindle DNA Binding Fat Cell Proliferation Meiotic Telomere Clustering
Tagcloud ?