BPI

Gene Name		bactericidal/permeability-increasing protein
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Integral Component Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Lipopolysaccharide Binding
	Biological Process	Immune Response Negative Regulation Of Interleukin-6 Production Negative Regulation Of Interleukin-8 Production Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Macrophage Activation Defense Response To Gram-negative Bacterium
Pathways
Drugs		Di-Stearoyl-3-Sn-Phosphatidylcholine
Diseases
GWAS
Protein-protein Interactions		1 interactors: PRSS2
Entrez ID		671
HPRD ID		00174
Ensembl ID		ENSG00000101425
Uniprot IDs		P17213
PDB IDs		1BP1 1EWF
Enriched GO Terms of Interacting Partners?		Collagen Catabolic Process Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process Extracellular Matrix Disassembly Digestion Positive Regulation Of Cell Growth Positive Regulation Of Growth Regulation Of Cell Growth Extracellular Matrix Organization Extracellular Structure Organization Positive Regulation Of Cell Adhesion
Tagcloud ?		acetate azurophilic bactericidal c5a elastase ex fmlp granule inducers lasted leukocytes lipopolysaccharide lipoteichoic lta magnitude mediator microbial myristate permeability phorbol pmnl polymorphonuclear potently release released started stored stz zymosan