SPOCK1

Description		SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Postsynaptic Density Sarcoplasm Extracellular Matrix Neuromuscular Junction Node Of Ranvier
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Cysteine-type Endopeptidase Inhibitor Activity Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Collagen Binding Metalloendopeptidase Inhibitor Activity Extracellular Matrix Binding
	Biological Process	Regulation Of Cell Growth Neuron Migration Cell Adhesion Nervous System Development Negative Regulation Of Cell-substrate Adhesion Negative Regulation Of Neuron Projection Development Central Nervous System Neuron Differentiation Neurogenesis
Pathways
Drugs
Diseases
GWAS		Body mass index ( 28552196) Bronchopulmonary dysplasia ( 23897914) HIV-1 susceptibility ( 25786224) Mathematical ability ( 28155865) Metabolite levels ( 23823483) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Response to quetiapine in schizophrenia ( 29503163) Weight ( 28552196)
Novel Interacting Genes		1 novel interacting genes: PDGFRA
Interacting Genes		6 interacting genes: BCL2L13 CREB3L1 MMP14 MMP2 MMP3 UBC
Entrez ID		6695
HPRD ID		11887
Ensembl ID		ENSG00000152377
Uniprot IDs		Q08629
PDB IDs
Enriched GO Terms of Interacting Partners?		Collagen Catabolic Process Extracellular Matrix Organization Extracellular Structure Organization Extracellular Matrix Disassembly Collagen Metabolic Process Endopeptidase Activity Luteinization Cellular Response To Amino Acid Stimulus Metalloendopeptidase Activity Cellular Response To UV-A Response To Oxidative Stress Cellular Response To Reactive Oxygen Species Skeletal System Morphogenesis Response To Amino Acid Response To UV-A Metallopeptidase Activity Serine-type Endopeptidase Activity Response To Reactive Oxygen Species Cellular Response To Oxidative Stress Embryonic Cranial Skeleton Morphogenesis Face Morphogenesis Endodermal Cell Differentiation Ovulation Cycle Process Cellular Response To Stress Cellular Response To Chemical Stress Ovarian Follicle Development Angiogenesis Cellular Response To Oxygen-containing Compound Response To Amyloid-beta Response To Estrogen Catabolic Process Regulation Of Cell Migration Regulation Of Cell Motility Macromolecule Catabolic Process Cellular Response To Genistein Negative Regulation Of GDF15-GFRAL Signaling Pathway Platelet-derived Growth Factor Alpha-receptor Activity Regulation Of Locomotion Extracellular Matrix Embryonic Skeletal System Morphogenesis Tissue Remodeling Cellular Response To UV Peptidase Activity Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Proteolysis Lung Development Cellular Response To Light Stimulus Cell Differentiation Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Platelet-derived Growth Factor Receptor-ligand Complex
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