UAP1

Description		UDP-N-acetylglucosamine pyrophosphorylase 1
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane
	Molecular Function	UDP-N-acetylglucosamine Diphosphorylase Activity Transferase Activity Transferase Activity, Transferring Phosphorus-containing Groups Nucleotidyltransferase Activity Identical Protein Binding UDP-N-acetylgalactosamine Diphosphorylase Activity Uridylyltransferase Activity Protein Serine Pyrophosphorylase Activity
	Biological Process	Immune System Process UDP-N-acetylglucosamine Biosynthetic Process Positive Regulation Of Type I Interferon Production Innate Immune Response Antiviral Innate Immune Response
Pathways		Synthesis of UDP-N-acetyl-glucosamine
Drugs		Uridine-Diphosphate-N-Acetylgalactosamine Uridine-Diphosphate-N-Acetylglucosamine
Diseases
GWAS
Novel Interacting Genes		2 novel interacting genes: DEDD RGS4
Interacting Genes		1 interacting genes: FBXL17
Entrez ID		6675
HPRD ID		04178
Ensembl ID		ENSG00000117143
Uniprot IDs		A0A140VKC0 Q16222
PDB IDs		1JV1 1JV3 1JVD 1JVG 6Z2F 8QH2
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Glycine Import Across Plasma Membrane Negative Regulation Of Dopamine Receptor Signaling Pathway Dorsal Root Ganglion Development Negative Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Negative Regulation Of Striated Muscle Cell Differentiation Negative Regulation Of Amino Acid Transport Response To Cocaine Positive Regulation Of Excitatory Postsynaptic Potential Tissue Development Ganglion Development G-protein Alpha-subunit Binding Negative Regulation Of Muscle Hypertrophy Response To Amphetamine Regulation Of Dopamine Receptor Signaling Pathway Negative Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Potassium Ion Transport Negative Regulation Of Organ Growth Positive Regulation Of Heart Contraction Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Heart Rate Negative Regulation Of Cardiac Muscle Tissue Growth Response To Amine Negative Regulation Of Cardiac Muscle Hypertrophy Decidualization Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Transcription By RNA Polymerase I Negative Regulation Of Transcription By RNA Polymerase I Neural Crest Cell Differentiation Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Modulation Of Excitatory Postsynaptic Potential Negative Regulation Of G Protein-coupled Receptor Signaling Pathway
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