SORD

Gene Name		sorbitol dehydrogenase
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Membrane Motile Cilium Mitochondrial Membrane Extracellular Vesicular Exosome
	Molecular Function	L-iditol 2-dehydrogenase Activity Zinc Ion Binding Carbohydrate Binding NAD Binding
	Biological Process	Glucose Metabolic Process Sorbitol Catabolic Process Sperm Motility Fructose Biosynthetic Process L-xylitol Catabolic Process L-xylitol Metabolic Process Oxidation-reduction Process
Pathways
Drugs		NADH Nicotinamide-Adenine-Dinucleotide Cp-166572, 2-Hydroxymethyl-4-(4-N,N-Dimethylaminosulfonyl-1-Piperazino)-Pyrimidine
Diseases
GWAS
Protein-protein Interactions		2 interactors: RELA SHBG
Entrez ID		6652
HPRD ID		01679
Ensembl ID
Uniprot IDs		Q00796
PDB IDs		1PL6 1PL7 1PL8
Enriched GO Terms of Interacting Partners?		Acetaldehyde Metabolic Process Primary Spermatocyte Growth Positive Regulation Of Schwann Cell Differentiation Regulation Of Schwann Cell Differentiation Response To Cobalamin Positive Regulation Of MiRNA Metabolic Process Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Positive Regulation Of Interleukin-12 Biosynthetic Process Cellular Response To Nicotine Regulation Of MiRNA Metabolic Process Regulation Of Interleukin-12 Biosynthetic Process Response To Muramyl Dipeptide Response To UV-B Membrane Protein Intracellular Domain Proteolysis Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Cellular Response To Interleukin-6 Positive Regulation Of Chondrocyte Differentiation Response To Interleukin-6 Membrane Protein Proteolysis Negative Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Glial Cell Differentiation Response To Morphine Response To Nicotine Cellular Response To Alkaloid Positive Regulation Of Cartilage Development Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway NIK/NF-kappaB Signaling Positive Regulation Of Interleukin-12 Production Response To Progesterone Positive Regulation Of Gliogenesis Toll-like Receptor 5 Signaling Pathway Cellular Defense Response Toll-like Receptor 10 Signaling Pathway Cellular Response To Interleukin-1 Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Cellular Response To Hydrogen Peroxide Toll-like Receptor 9 Signaling Pathway Regulation Of Insulin Receptor Signaling Pathway Regulation Of Interleukin-12 Production TRIF-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Cytokine Biosynthetic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Chondrocyte Differentiation MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Glial Cell Differentiation Cellular Aldehyde Metabolic Process Positive Regulation Of Type I Interferon Production
Tagcloud ?		adh alb albinism arbitrarily assortment backcrossing constitution duplicate electrophoretically fumarate glo glucosephosphate glyoxalase gpd homeologous hydratase intersubspecies isocitrate malic mannosephosphate midh mme mpi numbered phosphorylase provisionally sme sorbitol ssod