CYP4F12

Description		cytochrome P450 family 4 subfamily F member 12
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Apical Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Monooxygenase Activity Iron Ion Binding Protein Binding Arachidonate Epoxygenase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Flavin Or Flavoprotein As One Donor, And Incorporation Of One Atom Of Oxygen Alkane 1-monooxygenase Activity Heme Binding Metal Ion Binding Leukotriene-B4 20-monooxygenase Activity
	Biological Process	Very Long-chain Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Renal Water Homeostasis Pressure Natriuresis Lipid Metabolic Process Fatty Acid Metabolic Process Xenobiotic Metabolic Process Arachidonate Metabolic Process Epoxygenase P450 Pathway Leukotriene B4 Catabolic Process Vitamin E Metabolic Process Menaquinone Catabolic Process Phylloquinone Catabolic Process Sodium Ion Homeostasis
Pathways		Fatty acids Eicosanoids
Drugs
Diseases
GWAS		Glioma ( 34319593) LDL cholesterol levels ( 32203549)
Novel Interacting Genes		1 novel interacting genes: SLC44A2
Interacting Genes		5 interacting genes: CFTR HSPA6 MEOX2 SOD2 TIMMDC1
Entrez ID		66002
HPRD ID		07102
Ensembl ID		ENSG00000186204
Uniprot IDs		Q9HCS2
PDB IDs
Enriched GO Terms of Interacting Partners?		Enzyme Binding Positive Regulation Of Anion Channel Activity Positive Regulation Of Enamel Mineralization Transepithelial Water Transport Organic Hydroxy Compound Transport Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Multicellular Organismal-level Chemical Homeostasis Positive Regulation Of Monoatomic Anion Transport Somite Specification Response To Magnetism Regulation Of Membrane Hyperpolarization Positive Regulation Of Hydrogen Peroxide Biosynthetic Process Response To Isolation Stress Positive Regulation Of Vascular Associated Smooth Muscle Cell Differentiation Involved In Phenotypic Switching Detection Of Oxygen Negative Regulation Of Membrane Hyperpolarization Superoxide Dismutase Activity Acetylcholine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Erythrophore Differentiation Response To Silicon Dioxide Response To L-ascorbic Acid Ethanolamine Transport Ethanolamine Transmembrane Transporter Activity Positive Regulation Of Tooth Mineralization Cellular Heat Acclimation Response To Superoxide Chloride Channel Inhibitor Activity Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Response To Oxygen Radical Choline Transmembrane Transporter Activity Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Amelogenesis Choline Transport Response To Alcohol ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Intracellular Oxygen Homeostasis Positive Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process Hydrogen Peroxide Biosynthetic Process Positive Regulation Of Vascular Associated Smooth Muscle Cell Differentiation Response To Selenium Ion Amine Transport Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane Response To Manganese Ion
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