SLIT1

Description		slit guidance ligand 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Calcium Ion Binding Protein Binding Heparin Binding Heparan Sulfate Proteoglycan Binding Roundabout Binding
	Biological Process	Nuclear Migration Nervous System Development Axonogenesis Axon Guidance Motor Neuron Axon Guidance Spinal Cord Development Olfactory Bulb Development Chemorepulsion Involved In Embryonic Olfactory Bulb Interneuron Precursor Migration Tangential Migration From The Subventricular Zone To The Olfactory Bulb Telencephalon Cell Migration Cell Differentiation Retinal Ganglion Cell Axon Guidance Dorsal/ventral Axon Guidance Neuron Projection Morphogenesis Negative Regulation Of Axon Extension Involved In Axon Guidance Axon Extension Involved In Axon Guidance Forebrain Morphogenesis Negative Chemotaxis Negative Regulation Of Synapse Assembly
Pathways		Netrin-1 signaling Signaling by ROBO receptors Regulation of commissural axon pathfinding by SLIT and ROBO Regulation of cortical dendrite branching Regulation of expression of SLITs and ROBOs
Drugs
Diseases
GWAS		Bipolar disorder ( 28115744) Diastolic blood pressure (alcohol consumption interaction) ( 24376456) Mean arterial pressure (alcohol consumption interaction) ( 24376456) Obesity-related traits ( 23251661)
Interacting Genes		17 interacting genes: ADAMTSL4 ATN1 CHRDL2 CYSRT1 FHL5 FXR1 GPC1 HOXA1 KRTAP1-1 KRTAP10-8 KRTAP13-2 KRTAP13-3 MEOX2 MTNR1A ROBO1 TRIM42 ZNF620
Entrez ID		6585
HPRD ID		04773
Ensembl ID		ENSG00000187122
Uniprot IDs		A6H8V1 O75093
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament
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