BMP5

Name	bone morphogenetic protein 5
Structure	No pdb structure
Interactors	5 interactors: BMPR1A CHRDL2 FST MEOX2 NOG
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Vesicle
	Molecular Function	Cytokine Activity Protein Binding Growth Factor Activity BMP Receptor Binding
	Biological Process	Skeletal System Development Ossification Endocardial Cushion Formation Type B Pancreatic Cell Development Pericardium Morphogenesis Pattern Specification Process Heart Development Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Tissue Development Negative Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Steroid Biosynthetic Process Neural Fold Elevation Formation Cell Differentiation BMP Signaling Pathway Male Genitalia Development Hindbrain Development Negative Regulation Of Aldosterone Biosynthetic Process Regulation Of Cell Population Proliferation Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Ear Development Positive Regulation Of Transcription By RNA Polymerase II Cell Development Cardiac Muscle Tissue Development Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of Developmental Process Cartilage Development Pharyngeal System Development Positive Regulation Of SMAD Protein Signal Transduction Cardiac Septum Morphogenesis Chorio-allantoic Fusion Heart Trabecula Morphogenesis Negative Regulation Of Mononuclear Cell Migration Anterior Head Development Positive Regulation Of Dendrite Development Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Allantois Development Negative Regulation Of Cortisol Biosynthetic Process
GWAS	Colorectal cancer or advanced adenoma ( 30510241 ) Heel bone mineral density ( 28869591 30598549 ) Lean body mass ( 28552196 ) Schizophrenia ( 34099189 ) Zinc levels ( 26025379 )
Entrez ID	653
HPRD ID	00210
Ensembl ID	ENSG00000112175
Uniprot IDs	A8K694 M9VUD0 P22003
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Neural Plate Pattern Specification BMP Signaling Pathway Pattern Specification Process Ventricular Compact Myocardium Morphogenesis Cartilage Development Regulation Of BMP Signaling Pathway Pharyngeal Arch Artery Morphogenesis Endocardial Cushion Formation Somite Development Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Heart Trabecula Morphogenesis Epithelial Cell Proliferation BMP Binding Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Animal Organ Formation Cellular Response To BMP Stimulus Pituitary Gland Development Endoderm Development Cellular Response To Growth Factor Stimulus Ventricular Septum Morphogenesis Regulation Of Cardiac Muscle Cell Proliferation System Development Response To Growth Factor Negative Regulation Of Cell Migration Ventricular Cardiac Muscle Tissue Morphogenesis Mesoderm Formation Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Limb Development Embryonic Digit Morphogenesis Mesoderm Development Cardiac Muscle Tissue Morphogenesis Formation Of Primary Germ Layer Outflow Tract Morphogenesis Artery Morphogenesis Dorsal/ventral Pattern Formation Regulation Of Heart Growth Somatic Stem Cell Population Maintenance Negative Regulation Of BMP Signaling Pathway Odontogenesis Of Dentin-containing Tooth Regulation Of SMAD Protein Signal Transduction Cardiac Septum Morphogenesis Muscle Tissue Morphogenesis Roof Of Mouth Development Animal Organ Development Regulation Of Animal Organ Morphogenesis Regulation Of Neural Crest Cell Differentiation