SLC4A2

Name	solute carrier family 4 member 2
Structure
Novel Interactors	1 novel interactors: GET1
Interactors	3 interactors: ATXN1 CA2 EPB42
GO Annotations	Cellular Component	Plasma Membrane Focal Adhesion Membrane Basolateral Plasma Membrane Apical Plasma Membrane
	Molecular Function	Solute:inorganic Anion Antiporter Activity Protein Binding Monoatomic Anion Transmembrane Transporter Activity Antiporter Activity Enzyme Binding Transmembrane Transporter Activity Chloride:bicarbonate Antiporter Activity
	Biological Process	Monoatomic Ion Transport Monoatomic Anion Transport Spermatogenesis Inorganic Anion Transport Bicarbonate Transport Osteoclast Differentiation Regulation Of Actin Cytoskeleton Organization Negative Regulation Of CD8-positive, Alpha-beta T Cell Differentiation Regulation Of Bone Resorption Digestive Tract Development Regulation Of Intracellular PH Transmembrane Transport Positive Regulation Of Enamel Mineralization Amelogenesis Monoatomic Anion Transmembrane Transport Chloride Transmembrane Transport Negative Regulation Of CD8-positive, Alpha-beta T Cell Proliferation
Pathways	Bicarbonate transporters
GWAS	Eyebrow thickness ( 26926045 ) Heel bone mineral density ( 30598549 ) Mean corpuscular hemoglobin ( 32888494 )
Entrez ID	6522
HPRD ID	02728
Ensembl ID	ENSG00000164889
Uniprot IDs	P04920 Q59GF1
PDB IDs	8GV8 8GV9 8GVA 8GVC 8GVE 8GVF 8GVH 8JNI 8JNJ 8ZLE
GO Terms Enriched among Interactors ?	Regulation Of Biological Quality Positive Regulation Of Dipeptide Transmembrane Transport Cyanamide Hydratase Activity GET Complex Arylesterase Activity Positive Regulation Of Cellular PH Reduction Regulation Of Chloride Transport POZ Domain Binding Ankyrin-1 Complex Protein-glutamine Gamma-glutamyltransferase Activity Poly(G) Binding Otic Vesicle Development Animal Organ Development Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Hemoglobin Metabolic Process Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Nuclear Inclusion Body Regulation Of Monoatomic Anion Transport Carbonate Dehydratase Activity Carbon Dioxide Transport Positive Regulation Of Synaptic Transmission, GABAergic Tail-anchored Membrane Protein Insertion Into ER Membrane Monoatomic Ion Homeostasis Monoatomic Cation Homeostasis Angiotensin-activated Signaling Pathway Erythrocyte Maturation Poly(U) RNA Binding Positive Regulation Of Glial Cell Proliferation Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway One-carbon Compound Transport Multicellular Organismal-level Iron Ion Homeostasis Myelin Sheath Cortical Cytoskeleton Protein Targeting To ER Protein Insertion Into ER Membrane Regulation Of Synaptic Transmission, GABAergic Developmental Process Insulin-like Growth Factor Receptor Signaling Pathway Protein-membrane Adaptor Activity Establishment Of Protein Localization To Endoplasmic Reticulum