SCG5

Description		secretogranin V
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Secretory Granule
	Molecular Function	Enzyme Inhibitor Activity Protein Binding GTP Binding Enzyme Regulator Activity Unfolded Protein Binding
	Biological Process	Intracellular Protein Transport Neuropeptide Signaling Pathway Peptide Hormone Processing Regulation Of Hormone Secretion
Pathways
Drugs
Diseases
GWAS		A body shape index ( 34021172) Chin dimples ( 27182965) Colorectal cancer ( 21761138 24737748 25990418 30529582 31826910) Obesity-related traits ( 23251661) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		10 interacting genes: AGTR1 CCR2 FBXL17 KHDRBS1 MEOX2 NR1H2 PCSK2 UBQLN1 UBQLN2 UBQLN4
Entrez ID		6447
HPRD ID		01410
Ensembl ID		ENSG00000166922
Uniprot IDs		C9J650 C9JNY7 P05408
PDB IDs
Enriched GO Terms of Interacting Partners?		Polyubiquitin Modification-dependent Protein Binding Regulation Of Response To Endoplasmic Reticulum Stress Autophagosome Regulation Of Proteolysis Positive Regulation Of ERAD Pathway Negative Regulation Of Transport Regulation Of Transport Regulation Of ERAD Pathway Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Cellular Response To Stress Modification-dependent Protein Catabolic Process Positive Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Proteasomal Protein Catabolic Process Regulation Of Macroautophagy Ubiquitin-dependent Protein Catabolic Process Proteolysis Angiotensin Type I Receptor Activity Islet Amyloid Polypeptide Processing Positive Regulation Of Secretion Of Lysosomal Enzymes Grb2-Sos Complex Autophagy Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Store-operated Calcium Channel Activity Negative Regulation Of Eosinophil Degranulation Positive Regulation Of Astrocyte Chemotaxis T-helper 17 Cell Chemotaxis Chemokine (C-C Motif) Ligand 12 Binding Chemokine (C-C Motif) Ligand 2 Binding Negative Regulation Of Endocytosis Positive Regulation Of Metabolic Process Regulation Of Defense Response Bradykinin Receptor Binding Cytoplasmic Vesicle Enkephalin Processing Positive Regulation Of High-density Lipoprotein Particle Assembly Positive Regulation Of Pancreatic Juice Secretion Regulation Of Protein Metabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of G Protein-coupled Receptor Internalization Regulation Of Autophagy Nuclear Proteasome Complex Positive Regulation Of Immune Complex Clearance By Monocytes And Macrophages Positive Regulation Of Thymocyte Migration Positive Regulation Of CD8-positive, Alpha-beta T Cell Extravasation Chemokine (C-C Motif) Ligand 7 Binding Positive Regulation Of Hematopoietic Stem Cell Migration Regulation Of Astrocyte Chemotaxis ERAD Pathway Autophagosome Assembly Regulation Of Inflammatory Response
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