SOX17

Gene Name		SRY (sex determining region Y)-box 17
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Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex Nuclear Transcription Factor Complex
	Molecular Function	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Beta-catenin Binding Transcription Factor Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Angiogenesis Vasculogenesis Endoderm Formation Inner Cell Mass Cellular Morphogenesis Heart Looping Cardiogenic Plate Morphogenesis Embryonic Heart Tube Morphogenesis Outflow Tract Morphogenesis Negative Regulation Of Wnt Signaling Pathway Involved In Heart Development Regulation Of Transcription, DNA-templated Spermatogenesis Endodermal Cell Fate Determination Rostrocaudal Neural Tube Patterning Signal Transduction Involved In Regulation Of Gene Expression Negative Regulation Of Cell Growth Protein Destabilization Embryonic Heart Tube Development Cell Migration Involved In Gastrulation Negative Regulation Of Mesodermal Cell Fate Specification MRNA Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Differentiation Positive Regulation Of Protein Catabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Embryonic Development Embryonic Foregut Morphogenesis Positive Regulation Of Skeletal Muscle Tissue Development Stem Cell Fate Specification Protein Stabilization Canonical Wnt Signaling Pathway Endocardium Formation Regulation Of Transcription From RNA Polymerase II Promoter Involved In Definitive Endodermal Cell Fate Specification Cardiac Cell Fate Determination Heart Formation Endocardial Cell Differentiation Common Bile Duct Development Gall Bladder Development Endodermal Digestive Tract Morphogenesis Renal System Development Regulation Of Stem Cell Proliferation Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Stem Cell Division Regulation Of Cardiac Cell Fate Specification
Pathways
Drugs
Diseases
GWAS		Intracranial aneurysm ( 18997786 20364137)
Protein-protein Interactions		1 interactors: CTNNB1
Entrez ID		64321
HPRD ID		18085
Ensembl ID		ENSG00000164736
Uniprot IDs		Q9H6I2
PDB IDs		2YUL 4A3N
Enriched GO Terms of Interacting Partners?		Schwann Cell Proliferation Negative Regulation Of Mitotic Cell Cycle, Embryonic Cellular Response To Insulin-like Growth Factor Stimulus Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Cardiac Outflow Tract Cell Proliferation Glial Cell Fate Determination Oviduct Development Regulation Of Centriole-centriole Cohesion Renal Inner Medulla Development Renal Outer Medulla Development Mesenchymal Cell Proliferation Involved In Lung Development Positive Regulation Of Determination Of Dorsal Identity Embryonic Skeletal Limb Joint Morphogenesis Canonical Wnt Signaling Pathway Involved In Regulation Of Cell Proliferation Lung Induction Central Nervous System Vasculogenesis Trachea Formation Cellular Response To Indole-3-methanol Regulation Of Centromeric Sister Chromatid Cohesion Renal Vesicle Formation Regulation Of Mitotic Cell Cycle, Embryonic Negative Regulation Of Protein Sumoylation Positive Regulation Of Branching Involved In Lung Morphogenesis Regulation Of Secondary Heart Field Cardioblast Proliferation Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Branching Involved In Lung Morphogenesis Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Fungiform Papilla Formation Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Establishment Of Blood-brain Barrier Fungiform Papilla Morphogenesis Glial Cell Proliferation Metanephric Renal Vesicle Morphogenesis Endothelial Tube Morphogenesis Renal Vesicle Morphogenesis Sympathetic Ganglion Development Endodermal Cell Fate Commitment Fungiform Papilla Development Regulation Of Sister Chromatid Cohesion Neural Plate Development Positive Regulation Of Endothelial Cell Differentiation Mesenchymal Cell Proliferation Lung-associated Mesenchyme Development Mesenchymal To Epithelial Transition Epithelial Cell Differentiation Involved In Prostate Gland Development Trachea Morphogenesis Positive Regulation Of Glycoprotein Biosynthetic Process Genitalia Morphogenesis
Tagcloud ?		3p accordingly bodies brachyury cbx4 cbx7 chemicals ectodermal embryoid endodermal fgf5 foxa2 ideal markers meanwhile mebs mesodermal nanog nestin oct4 pcg perfluorooctane pfos pluripotency polycomb poses sma sox2 sulfonate