RNF25

Name	ring finger protein 25
Structure
Novel Interactors	1 novel interactors: CHPF
Interactors	10 interactors: KCTD21 MEOX2 RELA TRIM27 UBE2D1 UBE2D2 UBE2D4 UBE2E2 UBE2L6 UBE2U
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cytosolic Ribosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding NF-kappaB Binding Ubiquitin Protein Ligase Activity
	Biological Process	Translational Elongation Translational Termination Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Positive Regulation Of NF-kappaB Transcription Factor Activity Rescue Of Stalled Ribosome Protein K6-linked Ubiquitination Protein-RNA Covalent Cross-linking Repair
Pathways	Antigen processing: Ubiquitination & Proteasome degradation
GWAS	Male-pattern baldness ( 28196072 )
Entrez ID	64320
HPRD ID	09737
Ensembl ID	ENSG00000163481
Uniprot IDs	Q96BH1
PDB IDs	2DAY 2DMF 5D1K 5D1L 5D1M
GO Terms Enriched among Interactors ?	Ubiquitin Conjugating Enzyme Activity Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Post-translational Protein Modification Ubiquitin-protein Transferase Activity Protein Metabolic Process Modification-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Macromolecule Catabolic Process Protein Modification Process Transferase Activity Proteolysis Involved In Protein Catabolic Process ISG15 Transferase Activity ISG15-protein Conjugation Protein K63-linked Ubiquitination Macromolecule Metabolic Process Proteolysis Catabolic Process Ubiquitin-like Protein Transferase Activity Protein K11-linked Ubiquitination ATP Binding NF-kappaB P50/p65 Complex Ubiquitin Protein Ligase Activity Positive Regulation Of Schwann Cell Differentiation Response To Cobalamin N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase Activity Toll-like Receptor TLR6:TLR2 Signaling Pathway Regulation Of Schwann Cell Differentiation NF-kappaB Complex Prolactin Signaling Pathway Nucleotide Binding Somite Specification Postsynapse To Nucleus Signaling Pathway Histone Deacetylase Binding Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity HULC Complex