RNF25

Gene Name		ring finger protein 25
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Gene Ontology Annotations	Cellular Component	Nucleus Cytosol
	Molecular Function	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity NF-kappaB Binding
	Biological Process	Protein Ubiquitination Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		11 interactors: RELA TRIM27 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2L6 UBE2U
Entrez ID		64320
HPRD ID		09737
Ensembl ID		ENSG00000163481
Uniprot IDs		Q96BH1
PDB IDs		2DAY 2DMF
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Protein K48-linked Ubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K11-linked Ubiquitination Protein K63-linked Ubiquitination ISG15-protein Conjugation TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Cellular Protein Modification Process Toll-like Receptor 4 Signaling Pathway Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Protein Metabolic Process Toll-like Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Cellular Protein Metabolic Process Innate Immune Response Cellular Macromolecule Catabolic Process Positive Regulation Of Innate Immune Response Proteolysis Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Ubiquitin-dependent Protein Catabolic Process Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Innate Immune Response Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Immune Response Defense Response Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Type I Interferon Production Cellular Response To Oxygen Levels Negative Regulation Of Protein Catabolic Process Response To Stress Cellular Response To Stress Regulation Of Immune Response Immune Response-regulating Signaling Pathway Catabolic Process Regulation Of Cytokine Production Cellular Metabolic Process Negative Regulation Of Cytokine Production Mitotic Spindle Assembly Checkpoint Histone Ubiquitination
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