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MLST8
Gene Name
MTOR associated protein, LST8 homolog (S. cerevisiae)
Image
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytosol
Molecular Function
Protein Binding
Biological Process
Epidermal Growth Factor Receptor Signaling Pathway
Insulin Receptor Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Actin Filament Polymerization
T Cell Costimulation
Positive Regulation Of TOR Signaling
Regulation Of Rac GTPase Activity
Regulation Of Actin Cytoskeleton Organization
Cellular Response To Heat
Fc-epsilon Receptor Signaling Pathway
Innate Immune Response
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Phosphatidylinositol-mediated Signaling
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Regulation Of Cellular Response To Heat
Pathways
Signaling by the B Cell Receptor (BCR)
Signaling by FGFR in disease
mTOR signalling
Signaling by EGFRvIII in Cancer
Signaling by SCF-KIT
Downstream signaling events of B Cell Receptor (BCR)
DAP12 signaling
PI3K/AKT activation
PI-3K cascade
PKB-mediated events
PI3K Cascade
Signaling by PDGF
DAP12 interactions
GAB1 signalosome
CD28 co-stimulation
CD28 dependent PI3K/Akt signaling
Signaling by ERBB4
Role of LAT2/NTAL/LAB on calcium mobilization
Constitutive PI3K/AKT Signaling in Cancer
PI3K events in ERBB4 signaling
S6K1-mediated signalling
mTORC1-mediated signalling
Signaling by ERBB2
Signaling by EGFR
Signaling by VEGF
Downstream signal transduction
Fc epsilon receptor (FCERI) signaling
Signaling by EGFR in Cancer
PI3K/AKT Signaling in Cancer
Adaptive Immune System
Costimulation by the CD28 family
IRS-mediated signalling
PIP3 activates AKT signaling
mTOR signalling
S6K1-mediated signalling
mTORC1-mediated signalling
IGF1R signaling cascade
VEGFA-VEGFR2 Pathway
HSF1-dependent transactivation
IRS-related events triggered by IGF1R
PI3K events in ERBB2 signaling
Release of eIF4E
VEGFR2 mediated vascular permeability
Downstream signaling of activated FGFR
Signaling by Insulin receptor
Innate Immune System
Signalling by NGF
Insulin receptor signalling cascade
IRS-related events
Signaling by Ligand-Responsive EGFR Variants in Cancer
NGF signalling via TRKA from the plasma membrane
Cellular response to heat stress
Release of eIF4E
Signaling by Overexpressed Wild-Type EGFR in Cancer
Signaling by FGFR
IRS-mediated signalling
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
PKB-mediated events
PI3K Cascade
Drugs
Diseases
GWAS
Protein-protein Interactions
9 interactors:
A2M
AKT1S1
ATXN1
EIF4EBP1
MTOR
PRMT1
PRR5L
RPS6KB1
RPTOR
Entrez ID
64223
HPRD ID
17031
Ensembl ID
ENSG00000167965
Uniprot IDs
Q9BVC4
PDB IDs
4JSN
4JSP
4JSV
4JSX
4JT5
4JT6
Enriched GO Terms of Interacting Partners
?
TOR Signaling
Response To Heat
Regulation Of Cellular Response To Heat
Insulin Receptor Signaling Pathway
Response To Temperature Stimulus
Intracellular Signal Transduction
Cellular Response To Insulin Stimulus
Regulation Of Cellular Protein Metabolic Process
Cellular Response To Heat
Regulation Of Protein Metabolic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Signaling
Response To Insulin
Cell Communication
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Peptide
Positive Regulation Of Transcription From RNA Polymerase III Promoter
Enzyme Linked Receptor Protein Signaling Pathway
Response To Amino Acid
Regulation Of Signal Transduction
Negative Regulation Of Cell Size
Regulation Of Cell Size
Response To Peptide Hormone
Phosphatidylinositol-mediated Signaling
Cellular Response To Organonitrogen Compound
Regulation Of Signaling
Response To Peptide
Response To Abiotic Stimulus
Regulation Of Transcription From RNA Polymerase III Promoter
Negative Regulation Of Cellular Metabolic Process
Regulation Of Metabolic Process
Cellular Response To Hormone Stimulus
Signal Transduction
Regulation Of Phosphorylation
Response To Stimulus
Regulation Of Phosphorus Metabolic Process
Regulation Of Translation
Negative Regulation Of Cellular Protein Metabolic Process
Response To Organonitrogen Compound
Regulation Of Cellular Component Size
Regulation Of Intracellular Signal Transduction
Negative Regulation Of Protein Metabolic Process
Regulation Of TOR Signaling
Positive Regulation Of Endothelial Cell Proliferation
Cellular Response To Stimulus
Response To Hormone
Cellular Response To Organic Substance
Cell Surface Receptor Signaling Pathway
Regulation Of Translational Initiation
Positive Regulation Of Translation
Tagcloud
?
activates
akt
believed
deactivated
deregulates
drosophila
evaluates
existence
explained
gbetal
interacting
ischemic
lies
msin1
mtor
mtorc1
mtorc2
multiprotein
pras40
protor
raptor
representing
rictor
s6k1
ser473
stream
suppresses
threonine
tsc2