BHMT

Gene Name		betaine--homocysteine S-methyltransferase
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Protein Complex Extracellular Vesicular Exosome
	Molecular Function	Zinc Ion Binding S-adenosylmethionine-homocysteine S-methyltransferase Activity Protein Complex Binding Betaine-homocysteine S-methyltransferase Activity
	Biological Process	Sulfur Amino Acid Metabolic Process Protein Methylation Amino-acid Betaine Metabolic Process Amino-acid Betaine Catabolic Process Response To Organonitrogen Compound S-methylmethionine Cycle Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process S-adenosylmethionine Metabolic Process Regulation Of Homocysteine Metabolic Process L-methionine Salvage
Pathways		Sulfur amino acid metabolism Metabolism of amino acids and derivatives
Drugs		L-Methionine S-(D-Carboxybutyl)-L-Homocysteine Citric Acid
Diseases
GWAS		Blood trace element (Se levels) ( 23720494) Metabolite levels ( 23378610)
Protein-protein Interactions		5 interactors: ALG9 BBS1 BBS2 BBS4 LAMTOR3
Entrez ID		635
HPRD ID		04200
Ensembl ID		ENSG00000145692
Uniprot IDs		E5RJH0 Q93088
PDB IDs		1LT7 1LT8
Enriched GO Terms of Interacting Partners?		Nonmotile Primary Cilium Assembly Photoreceptor Cell Maintenance Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Retina Homeostasis Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Leptin-mediated Signaling Pathway Negative Regulation Of Appetite Cellular Response To Leptin Stimulus Regulation Of Microtubule-based Movement Cilium Assembly Striatum Development Response To Leptin Visual Perception Sensory Perception Of Light Stimulus Tissue Homeostasis Cilium Organization Regulation Of Response To Food Cilium Morphogenesis Regulation Of Appetite Subpallium Development Golgi To Plasma Membrane Protein Transport Multicellular Organismal Homeostasis Cell Projection Assembly Golgi To Plasma Membrane Transport Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Brain Morphogenesis Positive Regulation Of Multicellular Organism Growth Cellular Protein Localization Cellular Pigmentation Organelle Assembly Hippocampus Development Protein Localization To Organelle Establishment Of Protein Localization To Plasma Membrane Post-Golgi Vesicle-mediated Transport Limbic System Development Regulation Of Multicellular Organism Growth Protein Localization Pigmentation Fat Cell Differentiation Spermatid Development Sensory Perception Spermatid Differentiation Protein Localization To Plasma Membrane Cell Projection Morphogenesis Positive Regulation Of Developmental Growth Cerebral Cortex Development Cell Part Morphogenesis
Tagcloud ?		1236bp 3days 6days 6months abundances aestivation african annectens arousal betaine bhmt1 callorhinchus catalyses coding deleterious homocysteine lungfish methionine methyltransferase milii phases phylogenetic protopterus reconstruction returned tetrapods translationally unchanged unlike